DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and Serpini1

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	NP_446231.1	Gene:	Serpini1 / 116459	RGDID:	619896	Length:	410	Species:	Rattus norvegicus

Alignment Length:	445	Identity:	112/445 - (25%)
Similarity:	199/445 - (44%)	Gaps:	77/445 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVLLALLPVVTIAALDKPELSFLNEFSQIFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALL 70
            |.|:||..:||.||.....::             ::|:.:...:|......|:.|||.|...|:.
  Rat     7 LSLVALQSLVTGAAFPDETIA-------------EWSVNVYNHLRATGEDENILFSPLSIALAMG 58

  Fly    71 LAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDEFRW----------RQSPMELSSAN 125
            :....:...|.:|:..::             .|...:..:||.:          .:....:..||
  Rat    59 VMELGAQGSTLKEIRHSM-------------GYESLKSGEEFSFLRDFSSMVSAEEGQYVMKIAN 110

  Fly   126 RIFVDRTINVSNKFNTLL---YGA-TKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITP 186
            .:||....:::.:|..::   :.| ...:||..:.... ..||.|:.:.|::.::|::|..:...
  Rat   111 SLFVQNGFHINEEFLQMMKMYFNAEVNHVDFSENVAVA-NYINKWVENYTNSLLKDLVSPGDFDA 174

  Fly   187 HTMLVLANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKM------TIDEGLQS 245
            .|.|.|.||.|.||.|.|||:.|.|....|..::..:..:.||::.|.|..      :.:.|...
  Rat   175 VTHLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIY 239

  Fly   246 QIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSNKISLNRVISRLNADSVKKWFERALPQKI 310
            |::::||               ...:|||:::| :..::.|..:...|....:::|......||:
  Rat   240 QVLEIPY---------------EGDEISMMLVL-SRQEVPLATLEPLLKPQLIEEWANSVKKQKV 288

  Fly   311 ELSLPKFQFEQRLELTPILSLMGVNTMFTRNATFGDLTA--DPISLVIDDAQHLAKIKVDEVGST 373
            |:.||:|..||.::|..||..:||..:|.::|   :|||  |...|.:..|.|.:.|:|:|.||.
  Rat   289 EVYLPRFTVEQEIDLKDILKALGVTEIFIKDA---NLTAMSDKKELFLSKAVHKSFIEVNEEGSE 350

  Fly   374 AAAAT-ILLVSRSSRQPDPTKFN---CNHPFVFLIYDEKVDTILFAGVYSDPRQM 424
            ||.|: ::.:||.:     ..|.   .:|||:|||.:.|..||||.|....|..|
  Rat   351 AAVASGMIAISRMA-----VLFPQVIVDHPFLFLIKNRKTGTILFMGRVMHPETM 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	102/406 (25%)
Serpini1	NP_446231.1	neuroserpin	23..410	CDD:239003	104/429 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920