DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and LOC110439158

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_021329696.1	Gene:	LOC110439158 / 110439158	-ID:	-	Length:	412	Species:	Danio rerio

Alignment Length:	431	Identity:	109/431 - (25%)
Similarity:	182/431 - (42%)	Gaps:	73/431 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LDKPELSFLNEFSQIFKGERDFSLALMKQIREI--YPSGNLFFSPFSTYNALLLAYFSSSEQTER 82
            |.:|.:|  .:...:.....||:..|.|::.|.  |.|.|:|||||:...||......:...|::
Zfish    24 LQQPPIS--AKLPSLININNDFAFHLYKRLIESPDYQSKNIFFSPFTVSMALSKLTLGAGGDTKQ 86

  Fly    83 ELAQALNLGWALNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFNTLLYGAT 147
            :|...:....|:        ::..:....|   .|.:| ...||..||..|      .|.||.:.
Zfish    87 QLLSGIGYNSAI--------FSTEEMHQLF---HSLLE-DIGNRTGVDIDI------GTALYASD 133

  Fly   148 K--------------------ELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVL 192
            :                    .:||: ..|| :.:||.::.:|||.:|...:  :::...|::.|
Zfish   134 RFKPHSKFLEDMKEFYHTDGFTVDFR-VKET-VDQINKYVEEKTHGKINQAV--DDLEKDTLMFL 194

  Fly   193 ANAAYMKGQWLSQFKVEETALKPFFINEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYK 257
            ....|.||:|...|..|:|....|.|:::....|.|||:....|:..|..|..:::.|.|
Zfish   195 LTYIYFKGKWDKPFNPEKTCESTFHIDDKTTVPVQMMHQYEYLKVYYDAELSIKVLCLDY----- 254

  Fly   258 SKETHISTPESKSDISMIIILPNSNK-----ISLNRVISRLNADSVKKWFERALPQKIELSLPKF 317
                       ....||.:.:|:.:.     ..|...|||   ..::||...|..:|:::.:||.
Zfish   255 -----------NDSFSMFLAVPDVHMGRKTIEDLEMTISR---QHIEKWKRSAFERKVDIYVPKL 305

  Fly   318 QFEQRLELTPILSLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLV 382
            ..:....|..||..||:..||:..|.|..::.:.|  .|....|.|.:.:||.|:||||.|.:..
Zfish   306 SLKTSYFLNDILKGMGMADMFSDKADFTGVSEEKI--FISKVVHKATLDIDEKGTTAAAVTTVQF 368

  Fly   383 SRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQ 423
            .:.|..|..| .:.:.||:..|.|:..|.|||.|...:|.:
Zfish   369 RQLSYSPLST-LSFDRPFMIFITDQTNDNILFFGKVVNPNE 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	105/407 (26%)
LOC110439158	XP_021329696.1	alpha-1-antitrypsin_like	40..403	CDD:239011	105/406 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.110