DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn88Eb and serpinb10

DIOPT Version :9

Sequence 1:	NP_650427.1	Gene:	Spn88Eb / 41829	FlyBaseID:	FBgn0038299	Length:	426	Species:	Drosophila melanogaster
Sequence 2:	XP_031760330.1	Gene:	serpinb10 / 100497689	XenbaseID:	XB-GENE-5769609	Length:	374	Species:	Xenopus tropicalis

Alignment Length:	402	Identity:	105/402 - (26%)
Similarity:	192/402 - (47%)	Gaps:	44/402 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 IFKGERDFSLALMKQIREIYPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWA--LNK 96
            |.....:|::.::::|.:.....|:.||..|...:|.:.|..:...|..::.:||:....  ::.
Frog     3 ICTANNEFTIDVLREISKTAAGQNVVFSSMSIMISLAMVYLGAHGNTAADMGKALHFDEVEDVHA 67

  Fly    97 Q-QVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRT-------INVSNKFNTLLYGATKE-LDF 152
            | :||:...:....|        ..|::.|::|.::.       :...|.|    |||..| :||
Frog    68 QFRVLLKELMKNGND--------YTLTTVNKLFGEKKYYFLPTFLKAINAF----YGAPLEKVDF 120

  Fly   153 KNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETALKPFF 217
            .::||.....||.||.:||..:|:::|....|:|:|:|::||..|....|.:||....|:..||.
Frog   121 SSNPEATRSYINAWIQEKTKGKIQNLLPENSISPNTVLMVANTLYFLANWTTQFSEHATSKAPFT 185

  Fly   218 INEREQEMVYMMHKTGAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNSN 282
            :...||..|.||.....|.|...:.....:::|||              ....|:||:|:||:::
Frog   186 LITNEQIKVNMMATMNTFNMKRIKNPGMSVLELPY--------------GDTKDLSMVIMLPDNS 236

  Fly   283 KISLNRVISRLNADSVKKW--FERALPQKIELSLPKFQFEQRLELTPILSLMGVNTMFTRN-ATF 344
            .: |.:|...::.:::.||  .|......:.:.||:|:.|:...|..:||.:|:::.|::: |.|
Frog   237 TV-LTKVDREISYENLSKWTRSENMSSNYLAVYLPRFRMEKSFSLKKVLSSLGMSSAFSQSRANF 300

  Fly   345 GDLTADPISLVIDDAQHLAKIKVDEVGSTAAAATILLVSRSSRQPDPTKFNCNHPFVFLIYDEKV 409
            ..:.... .|.:.|..|...|:|:|.|:.||:||..::|..|...:  :|..:.||.|.|...|.
Frog   301 SGMGKQK-QLYVSDVHHKTFIEVNEKGTEAASATGSVMSIRSLANE--EFKADRPFHFFIRHNKT 362

  Fly   410 DTILFAGVYSDP 421
            :.||..|.:..|
Frog   363 NCILLYGKFYSP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn88Eb	NP_650427.1	SERPIN	37..418	CDD:238101	103/394 (26%)
serpinb10	XP_031760330.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010