DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and hnrnpua

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_694691.5	Gene:	hnrnpua / 566326	ZFINID:	ZDB-GENE-030131-3731	Length:	760	Species:	Danio rerio

Alignment Length:	336	Identity:	69/336 - (20%)
Similarity:	122/336 - (36%)	Gaps:	96/336 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 METESRIGPDLTIFDVDYTTTV--RVSSDRLALRS-------------QGSFNTVRANCCVYGGR 133
            :|.|.....|.|:....|...:  :||.||.:..|             :||:...:...|
Zfish   185 LEEEDEEFDDTTVCLDTYNCDLHFKVSRDRYSASSLTMESFAYLWAGGRGSYGVDKGKAC----- 244

  Fly   134 WMYEI---------HLHTKGV----MQIGWA-SNSCQFNENSGVGDTKSSYGYDGSKQQIWHIST 184
              :|:         |:.:||:    :.:||: :||...     :|:...||.:..:.::..:..|
Zfish   245 --FEMKVIEKIPVKHISSKGIEDHDVLVGWSLANSSYL-----LGEEAYSYAFSMTAKKTSNAVT 302

  Fly   185 KKYGDKWQIGDVIGVTIDVDKEVIE--YYRNGRSMGVAFN-KLEKGPGISFFAAISLGYTQGIEA 246
            :.||:.:...||:|..|:.|...:|  :.:||..:|.||. ..::..|...|..: |.:...:|.
Zfish   303 EDYGETFDENDVVGCFINFDGAEVEISFSKNGEDLGKAFTVSKDELKGKPLFPHV-LCHNCAVEF 366

  Fly   247 NFGNR--PFMYPVSGFQPLMARPILKLQRANLLMNYLVNLAGIFSKYNAQSGMAPTNGADARV-- 307
            |||.:  ||.....||..|...|                   :..:.....|  |.|..|..|
Zfish   367 NFGQQESPFFAQPDGFTLLQQIP-------------------VHDRIRGPKG--PENKKDCEVIV 410

  Fly   308 ------------STKKT-----VYCIFAT------LLIEKFTNEIFDPYIIEDVLLRK---ISSM 346
                        .||.|     .|.|..|      ::|.....::.|...:.::.||.   :...
Zfish   411 VVGLPGSGKTEWVTKHTEANPGKYNILGTDTILEKMMISTLKRQMKDVTKLLEISLRAPLFLGKF 475

  Fly   347 TNLASEKENSY 357
            ..:|:.|:.:|
Zfish   476 IEIAARKKRNY 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	31/143 (22%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
hnrnpua	XP_694691.5	SAP	6..40	CDD:128789
		SPRY_hnRNP	197..372	CDD:293942	41/187 (22%)
		NK	408..562	CDD:302627	14/79 (18%)
		AAA_33	408..552	CDD:290396	14/79 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900