DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and rspry1

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	NP_001038537.2	Gene:	rspry1 / 565154	ZFINID:	ZDB-GENE-061026-2	Length:	580	Species:	Danio rerio

Alignment Length:	234	Identity:	72/234 - (30%)
Similarity:	114/234 - (48%)	Gaps:	31/234 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LADLSVTKQMLIVRTW---LDDKFQQIQTDSNEEIRRLYME----------TESRIGPDLTIFDV 99
            :::..::.::.::.:|   ||...:|:...:...:..|:::          ..|.|...|...||
Zfish   267 VSESCISDRLSVLESWADNLDYLKRQVGFCAQWSLDNLFIKEGRQFTYEKVNLSNINAMLNSNDV 331

  Fly   100 -DYTTTVRVSSDRLALR-SQGSFNTVRANCCVYGGRWMYEIHLHTKGVMQIGWASNSCQF--NEN 160
             :|   :::|...|..| ...||.:||...||..|.|.||:.:.|.||||||||:...:|  :|.
Zfish   332 SEY---LKISPTGLEARCDASSFESVRCTFCVDSGVWYYEVTVITSGVMQIGWATKDSKFLNHEG 393

  Fly   161 SGVGDTKSSYGYDGSKQQIWHISTKKYGDK--WQIGDVIGVTIDVDKEVIEYYRNGRSM----GV 219
            .|:||.:.|..|||.:|.||:.:..|....  |:.||.||..:|:.|:.:.:|.||..:    .|
Zfish   394 YGIGDDEYSCAYDGCRQLIWYNARSKPHSHPCWKEGDAIGFLLDLSKKQMIFYLNGHQLPPEKQV 458

  Fly   220 AFNKLEKGPGISFFAAISLGYTQGIEANFGNRPFMYPVS 258
            .|:...     .||||.|....|..|.|||.:||.:|.|
Zfish   459 FFSATS-----GFFAAASFMSYQQCEFNFGAKPFRHPPS 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	50/134 (37%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
rspry1	NP_001038537.2	SPRY_RING	363..483	CDD:293941	46/124 (37%)
rspry1	NP_001038537.2	zf-C3HC4_3	527..572	CDD:290631
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	3	2.860