DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and hnrnpul1

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	NP_998436.1	Gene:	hnrnpul1 / 406555	ZFINID:	ZDB-GENE-040426-2432	Length:	784	Species:	Danio rerio

Alignment Length:	460	Identity:	94/460 - (20%)
Similarity:	168/460 - (36%)	Gaps:	148/460 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 EQVDHDNLYSDLDDDLEGANCSTVP---------DPRPAKLADLSVTKQMLI---------VRTW 63
            ||.|.:.:..:.:....|.:...||         |.:||.:..:|..:..:.         ::|
Zfish    62 EQSDQEQMAGEKESSEMGTDFPEVPNDESKIKSVDEQPATVETVSKEEHEVAPVKLKSEDDIKT- 125

  Fly    64 LDDKFQQIQTDSNEEIRRLYMETESRIGPDLTIF------------------------------- 97
             :::.|:.:..|..|........|.:..||....
Zfish   126 -EEQEQRPEASSEREALESQQTEECKTEPDRHSHHGHKRRYDEAHGNSHYDHREDKRSRSPQPSA 189

  Fly    98 ---DVDYTTTV------------RVSSDRLA---LRSQG---SFNTVRANCCVYGGRWMYEI--- 138
               |.|:..|:            :||.|..:   |..:|   .::..||...|..||..||:
Zfish   190 EEDDEDFDDTLVAIDTYNSDLHFKVSPDHCSGYPLTIEGFAYLWSGARATYGVNKGRVCYELKVK 254

  Fly   139 ------HLHTK----GVMQIGWASNSCQFNENSGVGDTKSSYGYDGSKQQIWHISTKKYGDKWQI 193
                  ||.:.    .|:::||:.:||    ::.:|:...||||.|:.::..:.....||:|:..
Zfish   255 EYISVKHLPSSEPDPHVVRVGWSLDSC----STQLGEEAFSYGYGGTGKKSTNYKFGDYGEKFGE 315

  Fly   194 GDVIGVTIDVDK-EVIE--YYRNGRSMGVAFN-KLEKGPGISFFAAISLGYTQGIEANFGNR--P 252
            ||:||..||.|. |.:|  :.:||:.:.|||. ..|:..|.:.|..: |.....:|.|||.|  |
Zfish   316 GDIIGCYIDFDSHEQVEMAFSKNGKWLDVAFRVSKEELAGQALFPHV-LVKNCAVEFNFGQREEP 379

  Fly   253 FMYPVSGFQPLMARPILKLQRANLLMNYLVNLAGIFSKYNAQSG-MAPTNGADARV-------ST 309
            :.....|:                      :..|..|..|...| :.|::.:|.:|       :.
Zfish   380 YFPLPDGY----------------------SFIGDVSLENRVRGTVGPSSKSDCQVLMMVGLPAC 422

  Fly   310 KKTVYCI-FATLLIEKFTNEIFDPYIIE-----------------DVLLRKISSMTN----LASE 352
            .||.:.. .|.:..:|..|.:....|:|                 |:|:::.:...|    :||.
Zfish   423 GKTTWAAKHAEMNPDKRFNILGTNAIMEKMKVMGLRRQRNYAGRWDILIQQATQCLNRLLQIASH 487

  Fly   353 KENSY 357
            |:.:|
Zfish   488 KKRNY 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	43/143 (30%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
hnrnpul1	NP_998436.1	SAP	5..39	CDD:128789
		SPRY_hnRNP	201..378	CDD:293942	51/181 (28%)
		AAA_33	413..557	CDD:290396	15/80 (19%)
		NK	413..>509	CDD:302627	15/80 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900