DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and CG30122

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	NP_001163196.1	Gene:	CG30122 / 37146	FlyBaseID:	FBgn0050122	Length:	1272	Species:	Drosophila melanogaster

Alignment Length:	242	Identity:	55/242 - (22%)
Similarity:	90/242 - (37%)	Gaps:	63/242 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 HDNLYSDLDDDLEGANCSTVPDPRPAKLADLSVTKQMLIVRTWLDDKFQQIQTDSNEEIRRLYME 85
            |.....|..:....|...|||:..|       ..::..:..:|||.                  :
  Fly   269 HRGSVGDKRESKAAAEERTVPEDEP-------TIEENKVGLSWLDS------------------D 308

  Fly    86 TESRIGPDLTIFDVDYTTTVRVSSDRLALRSQGSFNTVRANCCVYGGRWMYEIHLHTKGVMQIGW 150
            ...||.|      ..:.:...::|:..:|...|:    |||..|..|:..:|:.|..:.|.:
  Fly   309 LHLRIDP------TTFASAKPLTSEIYSLIWSGA----RANYGVREGKVCFEVRLSEESVPE--- 360

  Fly   151 ASNSCQFNENSGV----------------GDTKSSYGYDGSKQQIWHISTKKYGDKWQIGDVIGV 199
              ||..|.:...|                |:.:.|:||..:.::........||..:|:.||||.
  Fly   361 --NSHYFRDEPHVRGFRVGFSMPKSSLLLGEAEHSFGYCETGRKATQSEFTDYGKPYQLDDVIGC 423

  Fly   200 TIDVDKE--VIEYYRNGRSMGVAFNKLEKG----PGISFFAAISLGY 240
            .:|::.|  .|.|..||..:|||| :.||.    .|..|...::.||
  Fly   424 YLDLESEPCTINYTLNGEDLGVAF-EFEKSILGEEGALFPHIVTKGY 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	39/141 (28%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
CG30122	NP_001163196.1	SAP	6..40	CDD:280251
		SPRY_hnRNP	300..480	CDD:293942	48/204 (24%)
		PHA02664	<529..659	CDD:177447
		AAA_33	709..855	CDD:290396
		NK	709..>836	CDD:302627
		DUF1777	1033..>1104	CDD:285811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900