DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and Hnrnpul1

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_008757177.1	Gene:	Hnrnpul1 / 361522	RGDID:	1307456	Length:	860	Species:	Rattus norvegicus

Alignment Length:	419	Identity:	91/419 - (21%)
Similarity:	166/419 - (39%)	Gaps:	114/419 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DHDNLYSDLDDDLEGANCSTVPDPRPAKLADLSVTKQMLIVRTWLDDKFQQIQTDSN-------- 76
            :::::|.....|:|       |..:..:..:|....:.....::|..:..|::||..
  Rat   119 ENESVYDRRPLDME-------PPQQAYRPVELKTETKQEAPPSFLPPEASQLKTDRPQFQNRKRP 176

  Fly    77 -EEIR-RLYME-TESRIG----PDLTIFDVDYTTTV------------RVSSDRLA---LRSQG- 118
             ||.| |.|.| .|.|.|    |.....:.|:..|:            :|:.||.:   |..:|
  Rat   177 FEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGF 241

  Fly   119 --SFNTVRANCCVYGGRWMYEIHLHTK-------------GVMQIGWASNSCQFNENSGVGDTKS 168
              .::..||:..|..||..:|:.::.:             .|::|||:.:||    ::.:|:...
  Rat   242 AYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSC----STQLGEEPF 302

  Fly   169 SYGYDGSKQQIWHISTKKYGDKWQIGDVIGVTIDV----DKEVIEYYRNGRSMGVAFNKLEKGPG 229
            ||||.|:.::..:...:.||||:...||||...|.    |.| :.:.:||:.||:||...::..|
  Rat   303 SYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVE-LSFTKNGKWMGIAFRIQKEALG 366

  Fly   230 ISFFAAISLGYTQGIEANFGNR--PFMYPVSGFQPLMARPILKLQRANLLMNYLVNLAGIFSKYN 292
            ........|.....:|.|||.|  |:...:.||..:...|:.:..|..:
  Rat   367 GQALYPHVLVKNCAVEFNFGQRAEPYCSILPGFTFIQHLPLSERIRGTI---------------- 415

  Fly   293 AQSGMAPTNGADARV-------STKKTVYCI--FATLLIEKF----TNEIFDPYIIE-------- 336
                 .|.:.|:..:       :..||.:.|  .|:...:|:    ||.|.|...:.
  Rat   416 -----GPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNY 475

  Fly   337 ----DVLLRKISSMTN----LASEKENSY 357
                |||:::.:...|    :|:.|:.:|
  Rat   476 AGRWDVLIQQATQCLNRLIQIAARKKRNY 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	39/143 (27%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
Hnrnpul1	XP_008757177.1	SAP	3..37	CDD:128789
		SPRY_hnRNP	213..390	CDD:293942	47/181 (26%)
		AAA_33	425..570	CDD:290396	16/80 (20%)
		NK	425..>563	CDD:302627	16/80 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900