DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6752 and Hnrnpul2

DIOPT Version :9

Sequence 1:	NP_001247116.1	Gene:	CG6752 / 41826	FlyBaseID:	FBgn0038296	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	NP_001292149.1	Gene:	Hnrnpul2 / 309197	RGDID:	1562784	Length:	745	Species:	Rattus norvegicus

Alignment Length:	460	Identity:	98/460 - (21%)
Similarity:	176/460 - (38%)	Gaps:	130/460 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DHDNLYSDLDDDLEGANCSTVPDPRPAKLADLSVTKQMLIVRTWLDDKFQQ-------------- 70
            :|||...:.|...|.:...|.....|   .|.:|.:|.       ||:..:
  Rat   144 EHDNGKGEEDGPEERSGDETPGSEAP---GDKAVEEQG-------DDQDSEKSKPAGSDGERRGV 198

  Fly    71 -IQTDSNEEIRRLYME-------TESRIGP-----------DLTIFDVD-YTTTV--RVSSDRLA 113
             .|.|..:|..|.|.|       :.|:..|           |.|:.::| ||:.:  ::|.||..
  Rat   199 KRQRDEKDEHGRAYYEFREEAYHSRSKSPPPPEEEAKDEEEDQTLVNLDTYTSDLHFQISKDRYG 263

  Fly   114 ---LRSQGSFNTVRANCCVYGGRWMYEIHLHTKG----------------------VMQIGWASN 153
               |.|: .|.|:.:     |.|..|.:   |||                      ::::||:.:
  Rat   264 GQPLFSE-KFPTLWS-----GARSTYGV---TKGKVCFEAKVTQNLPMKEGCTEVSLLRVGWSID 319

  Fly   154 -SCQFNENSGVGDTKSSYGYDGSKQQIWHISTKKYGDKWQIGDVIGVTIDVDKEVIE--YYRNGR 215
             ||     |.:|:.:.|||:||...:..:...:::|..:...||||...:.:...:|  :.:||.
  Rat   320 FSC-----SQLGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETGEVELSFSKNGE 379

  Fly   216 SMGVAFNKLEKGPGISFFAAISLGYTQGIEANFGNR--PFMYPVSGFQPLMARPILK-------- 270
            .:||||...::..|........|.....||.|||.:  ||..|...|..:.|.|:.:
  Rat   380 DLGVAFRISKESLGDRALLPHVLCKNCVIELNFGQKEEPFFPPPEEFVFIHAVPVEERVRTAVPP 444

  Fly   271 --LQRANLLMNYLVNLAGIFSKYNAQSGMAPTNGADARVSTKKTVYCIFA-TLLIEKFTNEIFDP 332
              ::...:::  :|.|.|        ||........|:.:.:|....:.| |:|.:.....:.:|
  Rat   445 KTIEECEVIL--MVGLPG--------SGKTQWALKYAKENPEKRYNVLGAETVLTQMRMKGLEEP 499

  Fly   333 YI---IEDVLLRK----ISSMTNLASEKENSYSVLHGLLSLFWNYMEGDEIKFVLRKLVNALLGT 390
            .:   ..|:|:::    :|.:..:||..:.::     :|.....|..|...|.:|.|       |
  Rat   500 EMDPKSRDLLVQQASQCLSKLVQIASRSKRNF-----ILDQCNVYNSGQRRKLLLFK-------T 552

  Fly   391 FTHTI 395
            |:..:
  Rat   553 FSRKV 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6752	NP_001247116.1	SPRY_RNF123	122..249	CDD:293940	35/151 (23%)
CG6752	NP_001247116.1	zf-C3HC4_3	1261..1309	CDD:290631
Hnrnpul2	NP_001292149.1	SAP	3..37	CDD:128789
		SPRY_hnRNP	244..415	CDD:293942	46/184 (25%)
		NK	452..>634	CDD:302627	24/128 (19%)
		AAA_33	452..597	CDD:290396	24/128 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2242
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900