Protein Alignment Gyc88E and Gycbeta100B

DIOPT Version :10

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_524603.2
• Gene: Gycbeta100B / 43682
• FlyBaseID: FBgn0013973
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 860
• Identity: 242/860 - (28%)
• Similarity: 381/860 - (44%)
• Gaps: 222/860 - (25%)

  Fly     1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGID-SPSFSVHQVYPENLLQKLAKKAQQVLGVSERD 64
            |||.:...|...:...:|||.||.|:::|.:. ...|.|.|:|.:.:...|...|.::|.:...|
  Fly     1 MYGFVNYALELLVLKHFGEEIWEKIKKKAMVSMEGQFLVRQIYDDEITYNLIGAAVEILNIPADD 65

  Fly    65 FMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQG- 128
            .::..|..|..|....|||::|.|||...||||..||.||::|...||.||||||.|..  |.|
  Fly    66 ILELFGKTFFEFCQDSGYDKILQVLGATPRDFLQNLDALHDHLGTLYPGMRAPSFRCTE--KDGE 128

  Fly   129 LTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVR-------------------EEILFDTV 174
            |.|||.|:|.|..:..:|.::.||...:..|:.|::|:                   :::|.|.|
  Fly   129 LLLHYYSERPGLEHIVIGIVKAVASKLHGVEVEIDIVKRKGEPIDEAEKERAIARENQQLLEDAV 193

  Fly   175 HVTFQLTFDNRAFTLA----------------------------------------------SLA 193
            ..|   |..:....||                                              |:|
  Fly   194 ATT---TTGSATVVLAPSSDAERNNNHNGSNGSNNNGMANNGNTVNVNNNNDGQQIASETDPSIA 255

  Fly   194 MT--------------REEKHLPISA----------HVLF------------------------- 209
            ::              :|:|.|.:..          ||.|
  Fly   256 LSTCPIAQDSFDCDGDKEQKCLRLLKNKSDDIERYDHVQFLIREINVAAKSQVDAKKDEVPDDME 320

  Fly   210 --------------EIFPFCMVFGADMVVRSIGNSLMVILPELLGK--KITAWFDLVRPLIAFKF 258
                          ::|||.::|...|.:...|.::..::|.:..:  .:....:.:||.:...|
  Fly   321 FLCEAPLISPATFCKVFPFHLMFDRQMKIVQAGKAVSRVIPRVAEENCSLIEVVEAIRPHLQLNF 385

  Fly   259 QTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPV 323
            :.||:..|.|:.|.|         .|.....:||     ::.|||||||:|:.....|:|...|.
  Fly   386 ENILSHINTIYVLQT---------RQGAMSSRHE-----QRFLRLKGQMMYIPETDRILFQCYPS 436

  Fly   324 MPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRT 388
            :.:|..|...||||:|:.:||.:|||:|...:...|.||..:.| ..:.||:::.|.|:.|.::|
  Fly   437 VMNLDDLTKKGLYISDVPLHDAARDLVLLSEKFEAEYKLTKNLE-MLTDKLQQTFRDLESEKQKT 500

  Fly   389 DELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRIT----PMEVVSMLNAM 449
            |.|||.::||.||:.||. :.|:.. :.:|||:::||.||.|.:.|:..|    .|::|.|||.:
  Fly   501 DRLLYSVLPKSVANELRH-QRPVPP-KRYDSVTLMFSGIVGFGQYCAANTDPDGAMKIVKMLNEL 563

  Fly   450 YSIFDKLTE--RN-SVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPSTGQH 511
            |::||.||:  || :||||||:||.||.|:|.||...:||:.:..:||||:|...::|..|  ..
  Fly   564 YTVFDALTDSKRNLNVYKVETVGDKYMAVSGLPDHCEDHAKCMARVALDMMDMAKNVKMGS--NP 626

  Fly   512 LRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLI------GPN 570
            ::|.:|:|||.||.|::|.::|||||||:|||..||.|:|.:..::::||.|..|:      ..:
  Fly   627 VQITIGIHSGEVVTGVIGNRVPRYCLFGNTVNLTSRTETTGVPGRINVSEETYRLLCMAINQDDS 691

  Fly   571 YKIIERGEIDVKGKGTMGTYWLEERENRLPLQLTAALQVHPLSPVPPTPTPKTKAIMPPVSKPLT 635
            :.:..||.:.:|||.|....|...|.....|..|        |....:......::..|:.:|.|
  Fly   692 FHLEYRGPVIMKGKPTPMDCWFLTRATSSILGGT--------SSTGGSGGGGNGSLDSPLLQPAT 748

  Fly   636 PMMPVSVSLAASMPTSNVPAVDVMASSSSISGLALTAAAAAHMSLHHQAVVAEALTGASVEVALP 700
            |                                  ||.||..:     .|||:...|.:
  Fly   749 P----------------------------------TAGAATPI-----PVVAQRAAGHA------ 768

  Fly   701 SVASGATGAAAGGGA 715
            ||:..::....||||
  Fly   769 SVSRTSSAGGGGGGA 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..163	CDD:462233	59/162 (36%)
		HNOBA	201..404	CDD:462234	65/253 (26%)
		CYCc	383..571	CDD:214485	85/200 (43%)
		PHA03307	794..>955	CDD:223039
Gycbeta100B	NP_524603.2	HNOB	2..164	CDD:462233	60/163 (37%)
		HNOBA	326..516	CDD:462234	61/204 (30%)
		Guanylate_cyc	522..714	CDD:425528	79/194 (41%)