Protein Alignment Gyc88E and Gycalpha99B

DIOPT Version :10

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_477088.2
• Gene: Gycalpha99B / 43493
• FlyBaseID: FBgn0013972
• Length: 676
• Species: Drosophila melanogaster
• Alignment Length: 653
• Identity: 185/653 - (28%)
• Similarity: 308/653 - (47%)
• Gaps: 107/653 - (16%)

  Fly     7 ENLSEYIKSVYGE--EKWEDIRRQAGIDSPSFSVHQVYP-----ENLLQKLAK-KAQQVL----- 58
            |:|:..:.|:..:  :.|.:|.: ..:|..:|.....|.     :.||.|:.: .|.::|
  Fly    56 EDLNTAVTSLVAKYRQNWPNIHK-LKLDPQTFKSCANYDYLADIQELLLKMDEASASEILVLLGE 119

  Fly    59 --------GVSERDFMDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMR 115
                    |:.||.|                     ..||..:::||..||.:::.||.....:.
  Fly   120 ELITCCCTGIIERAF---------------------RCLGTDLQEFLGSLDGVYDVLKLQEEDVT 163

  Fly   116 APSFICENETKQGLTLHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQL 180
            ...|:|..|.:    |.:.|:|....:..:|.::.:.|..|..:::|::...|.........|.|
  Fly   164 DTGFVCAGEGE----LIFTSERPVIAWLLLGSLKALTRMLYKVDVNIKIEPVEGDARRYRYLFSL 224

  Fly   181 TFDNRAFTL----ASLAMTREE----------KHLPISAHVLFEIFPFCMVFGADMVVRSIGNSL 231
            ..||....|    .|::.|..|          ..|.:::....::||:..:....:.:..:|...
  Fly   225 VKDNSQTMLMGRPTSVSKTIPETVQRSNSSNASDLQMNSSSFCKMFPWHFIMNEQLELVQLGRGF 289

  Fly   232 MVILPELL---GKKITAWFDLVRPL-IAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHE 292
            ..:....:   |.:.|.:||..||. :..||:.|:.||...| |:.::......|.
  Fly   290 SKLYKPYMADFGCQATTYFDFKRPKGLTMKFRDIVRRTYTPF-LIGLNNPPGAVDF--------- 344

  Fly   293 DGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQS 357
                |...|.:|||||:......::|:|:|.:..|..|...||:|:|:.:||.:|:::|.|.|..
  Fly   345 ----PAIGLEIKGQMVHCPESNSLLFIGSPFLDGLDGLTCNGLFISDIPLHDATREVILVGEQAR 405

  Fly   358 VELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSI 422
            .:..|....::.|: .:||:...:.:|.::...||:.:.|.::|::|..|.: || .:.:..|:|
  Fly   406 AQDGLRRRMDKIKN-SIEEANSAVTKERKKNVSLLHLIFPAEIAEKLWLGSS-ID-AKTYPDVTI 467

  Fly   423 LFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAE 487
            ||||||.||.||||.||..|:|||..:|..||:..:...|||||||||||.|.:|........|.
  Fly   468 LFSDIVGFTSICSRATPFMVISMLEGLYKDFDEFCDFFDVYKVETIGDAYCVASGLHRASIYDAH 532

  Fly   488 RVCDMALDMVDA----ITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRM 548
            :|..|||.|:||    ||     ..|:.:::|:|:|:|.|:||:||.|||||||||.:|..|::.
  Fly   533 KVAWMALKMIDACSKHIT-----HDGEQIKMRIGLHTGTVLAGVVGRKMPRYCLFGHSVTIANKF 592

  Fly   549 ESTSIAMKVHISESTKVLI----GPNYKIIERG------EIDVKGKGTMGTYWLEEREN-----R 598
            ||.|.|:|:::|.:||..:    |..:::..|.      |....| ||...|:||...|     .
  Fly   593 ESGSEALKINVSPTTKDWLTKHEGFEFELQPRDPSFLPKEFPNPG-GTETCYFLESFRNPALDSE 656

  Fly   599 LPL 601
            |||
  Fly   657 LPL 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..163	CDD:462233	34/176 (19%)
		HNOBA	201..404	CDD:462234	49/206 (24%)
		CYCc	383..571	CDD:214485	85/195 (44%)
		PHA03307	794..>955	CDD:223039
Gycalpha99B	NP_477088.2	HNOB	<109..208	CDD:462233	24/123 (20%)
		HNOBA	259..451	CDD:462234	49/206 (24%)
		Guanylate_cyc	457..647	CDD:425528	85/196 (43%)