DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc88E and CG32301

DIOPT Version :9

Sequence 1:	NP_001036711.1	Gene:	Gyc88E / 41825	FlyBaseID:	FBgn0038295	Length:	1097	Species:	Drosophila melanogaster
Sequence 2:	NP_728724.2	Gene:	CG32301 / 38285	FlyBaseID:	FBgn0052301	Length:	1111	Species:	Drosophila melanogaster

Alignment Length:	434	Identity:	100/434 - (23%)
Similarity:	181/434 - (41%)	Gaps:	100/434 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   189 LASLAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKKITAWF-DLVRP 252
            |.:|.:|..:..|||   ..|.  ||.:|...|.||..:   :.::.|....|...|:| .|...
  Fly   116 LMALLLTAMDLILPI---CYFR--PFSLVPSYDHVVIVL---IYLMFPIAFVKNGRAYFLGLAVS 172

  Fly   253 LIAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIM 317
            |..|.:..::::      :.|:|.|.|                     |...|..::..| .:.|
  Fly   173 LFYFGYMALIDK------ISTLDKVWE---------------------LTAYGAYLFFLN-MLCM 209

  Fly   318 FLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLD 382
            ||......::.|.|.:...:                ..|::..::|:.:|:
  Fly   210 FLSRFQEYNMRSGILSRYQV----------------VYQNLVFQMAMKEEK-------------- 244

  Fly   383 EEMRRTDELLYQMIPKQVADRLRRG------ENPID------TCEMF----DSVSILFSDIVTFT 431
                   .||..:||..:|..|:..      |:|.:      |..:|    ..||||.:|:|.||
  Fly   245 -------ALLDSIIPVTLARSLQDAIASHIEEDPSNLMPFTKTRHLFMEPHPEVSILEADMVDFT 302

  Fly   432 EICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDM 496
            .:.:.:...::|::|:.::..||.....|...:::.:||:|..|.|.|.....||....:.||||
  Fly   303 GLTTTMEVSDLVAILHELFVSFDLAANHNRATRIKFLGDSYTCVTGIPSYFPTHANACVNQALDM 367

  Fly   497 VDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISE 561
            ::...:: .....:.:.:|:|||||.::|||:||...::.::...|:..:|:||:.:...||||.
  Fly   368 IEISREV-SKRRNKKIDLRIGVHSGEILAGIIGLTKWQFDIWSKDVDITNRLESSGLPGMVHISS 431

  Fly   562 STKVLIGPNYKIIERGEIDVK-----GKGTMGTYWLEERENRLP 600
            .|..|: .|:.:.|.|....|     .:..:.||.:   .:|||
  Fly   432 RTLGLL-DNHYVYEEGTDTAKLDPLLQRSNLSTYLI---RSRLP 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572
		HNOBA	201..404	CDD:311573	37/203 (18%)
		CYCc	383..571	CDD:214485	56/203 (28%)
		Herpes_ICP4_C	794..>955	CDD:332854
CG32301	NP_728724.2	Nucleotidyl_cyc_III	283..439	CDD:299850	47/157 (30%)
		CYCc	812..1051	CDD:214485
		Nucleotidyl_cyc_III	841..1076	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.830