| Sequence 1: | NP_001036711.1 | Gene: | Gyc88E / 41825 | FlyBaseID: | FBgn0038295 | Length: | 1097 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_055835.2 | Gene: | PHLPP2 / 23035 | HGNCID: | 29149 | Length: | 1323 | Species: | Homo sapiens |
| Alignment Length: | 1270 | Identity: | 230/1270 - (18%) |
|---|---|---|---|
| Similarity: | 379/1270 - (29%) | Gaps: | 513/1270 - (40%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 2 YGLLLENLSEYIKSVYGEEKWEDIRRQAG---------IDSPSFSVHQVYPENLLQKLAKKAQQV 57
Fly 58 LGVSERDFMDQMGVYFVGFVGQYGYDRVLSVLG-RHMRDFL-----NGLDNLHEY-----LKFSY 111
Fly 112 PRMRA-PSFICENETKQGLTLH-------------------------------------YRSKRR 138
Fly 139 GFVYYTMGQIREV---------------------------ARYFYHKEM---HIELVREEILFDT 173
Fly 174 VHVTFQLTFDNRA--FTLASLAMTREEKH--------LPISAHVLFEIF--------------PF 214
Fly 215 CMVFGADMVVRSIGNSLMVILPELL--GKKITAW---FDL-----VRPLIAFKFQTIL---NRTN 266
Fly 267 NIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYM-----------------ENWR 314
Fly 315 MIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMR 379
Fly 380 LLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEI------CSRIT 438
Fly 439 PMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDL 503
Fly 504 KD-----PSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISEST 563
Fly 564 KVLIGPNYKIIERGEIDVKGKGTMGTYWLEERENRLP--LQLTAALQVHPLSPVPPTPTPKTKAI 626
Fly 627 MPPVSKPLTPMMPVSVSLAASMPTSNVPAVDVMASSSSISGLALTAAAAAHMSLHHQAVVAEALT 691
Fly 692 GASV-------EVALPSVASGATGAAAG--------GGAPSDDRNSRIYSPVTFKDVARRSVANS 741
Fly 742 PVRSCAQPDQERRRESRSNSTGHVFMRTPSEIFGSLILDTEEFL-EDLQISRSSLANNNNNQSPC 805
Fly 806 ----GFSPTPPFRIGSAPPKPRPSNPDKFTPEELAAMDQLTPPSTAPARETASCSSASLDRDKAT 866
Fly 867 KLKKITFSNSSSLDATTPTALAAVVCPMRTK--SPPMAVAPVMHM---VQASTSKGDG-QRPGSK 925
Fly 926 DSVSSISLHSPPPHRSNSAPARPHSMSKAARKAFLAAKQTKAMEKLDKMIEEVQEVESQSVAKAA 990
Fly 991 NMRLALYGHDGGG-DLAAGGCPLFLPPPPQQ------------QQQQQQSLMPSSISDSGLCSHG 1042
Fly 1043 HSHAPSCHHMDPKMTNSQSFQHSPRGGITHQCCSG 1077 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Gyc88E | NP_001036711.1 | HNOB | 2..164 | CDD:311572 | 39/249 (16%) |
| HNOBA | 201..404 | CDD:311573 | 52/246 (21%) | ||
| CYCc | 383..571 | CDD:214485 | 35/198 (18%) | ||
| Herpes_ICP4_C | 794..>955 | CDD:332854 | 34/170 (20%) | ||
| PHLPP2 | NP_055835.2 | PH_PHLPP-like | 149..243 | CDD:270131 | 7/26 (27%) |
| LRR 1 | 250..271 | 6/55 (11%) | |||
| leucine-rich repeat | 253..273 | CDD:275380 | 7/54 (13%) | ||
| LRR 2 | 273..296 | 7/24 (29%) | |||
| leucine-rich repeat | 274..300 | CDD:275380 | 8/27 (30%) | ||
| LRR 3 | 300..321 | 4/20 (20%) | |||
| leucine-rich repeat | 301..323 | CDD:275380 | 5/21 (24%) | ||
| LRR_RI | 313..606 | CDD:238064 | 53/305 (17%) | ||
| LRR_8 | 322..380 | CDD:290566 | 4/57 (7%) | ||
| LRR 4 | 323..344 | 3/20 (15%) | |||
| leucine-rich repeat | 324..346 | CDD:275380 | 2/21 (10%) | ||
| LRR 5 | 346..368 | 0/21 (0%) | |||
| leucine-rich repeat | 347..369 | CDD:275380 | 0/21 (0%) | ||
| LRR 6 | 369..390 | 5/20 (25%) | |||
| leucine-rich repeat | 370..416 | CDD:275380 | 5/45 (11%) | ||
| LRR 7 | 392..412 | 0/19 (0%) | |||
| LRR 8 | 416..439 | 4/22 (18%) | |||
| leucine-rich repeat | 418..440 | CDD:275380 | 4/21 (19%) | ||
| LRR 9 | 440..460 | 7/19 (37%) | |||
| leucine-rich repeat | 442..461 | CDD:275380 | 7/19 (37%) | ||
| LRR 10 | 461..480 | 4/18 (22%) | |||
| leucine-rich repeat | 462..481 | CDD:275380 | 4/18 (22%) | ||
| LRR 11 | 481..502 | 1/20 (5%) | |||
| leucine-rich repeat | 482..503 | CDD:275380 | 2/20 (10%) | ||
| LRR 12 | 503..524 | 3/26 (12%) | |||
| leucine-rich repeat | 504..526 | CDD:275380 | 3/27 (11%) | ||
| LRR 13 | 526..547 | 6/20 (30%) | |||
| leucine-rich repeat | 527..549 | CDD:275380 | 5/21 (24%) | ||
| LRR_8 | 549..606 | CDD:290566 | 14/62 (23%) | ||
| LRR 14 | 549..570 | 4/20 (20%) | |||
| leucine-rich repeat | 550..565 | CDD:275380 | 2/14 (14%) | ||
| LRR 15 | 571..592 | 6/22 (27%) | |||
| leucine-rich repeat | 572..595 | CDD:275380 | 6/24 (25%) | ||
| LRR 16 | 595..616 | 2/24 (8%) | |||
| leucine-rich repeat | 596..645 | CDD:275380 | 11/58 (19%) | ||
| LRR 17 | 621..644 | 7/28 (25%) | |||
| LRR_8 | 645..703 | CDD:290566 | 17/75 (23%) | ||
| LRR_4 | 645..685 | CDD:289563 | 13/52 (25%) | ||
| LRR 18 | 645..666 | 6/27 (22%) | |||
| leucine-rich repeat | 646..669 | CDD:275380 | 8/29 (28%) | ||
| LRR 19 | 669..690 | 6/26 (23%) | |||
| leucine-rich repeat | 670..692 | CDD:275380 | 6/27 (22%) | ||
| LRR 20 | 692..713 | 4/25 (16%) | |||
| leucine-rich repeat | 693..714 | CDD:275380 | 3/20 (15%) | ||
| LRR 21 | 714..735 | 3/20 (15%) | |||
| leucine-rich repeat | 715..734 | CDD:275380 | 3/18 (17%) | ||
| LRR 22 | 737..758 | 5/46 (11%) | |||
| leucine-rich repeat | 738..764 | CDD:275380 | 7/51 (14%) | ||
| PP2Cc | 784..1033 | CDD:238083 | 67/415 (16%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1060..1157 | 29/134 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1285..1323 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2114 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||