Protein Alignment Gyc88E and gcy-37

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_500171.2
• Gene: gcy-37 / 191658
• WormBaseID: WBGene00001557
• Length: 708
• Species: Caenorhabditis elegans
• Alignment Length: 633
• Identity: 170/633 - (26%)
• Similarity: 325/633 - (51%)
• Gaps: 74/633 - (11%)

  Fly     9 LSEYIKSVYGEEKWEDIRRQAGI-DSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDFMDQMGVY 72
            :|..|...||.|..|:|.|:||. :...|.:...|.:....::.:.|..|||:|..|..:..|.:
 Worm     9 VSALILRKYGPEVLEEILRKAGYQEDIKFDIQCYYDDTETMRIFRVAATVLGLSVDDMWEMYGEF 73

  Fly    73 FVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYL-KFSY-PRMRAPSFICENETKQGLTLHYRS 135
            .:....:.|:.::|..:..::::||:.|:::|.:: :.:: ..|:.|:|.||...:.||.|||.|
 Worm    74 LITHACETGWQKMLFCMANNLQEFLDNLNSMHYFIDQIAFKSEMKGPTFQCEPFGESGLKLHYFS 138

  Fly   136 KRRGFVYYTMGQIREVARYFYHKEMHIELV------REEILFDTVHVTFQLTFDNR--------- 185
            .|:|......|.:|:.||..:..::.:.::      |:..:.:  ||.|.:..|:.
 Worm   139 FRQGLFPIVKGLVRKTARTLFEMDVKVCMLERNQERRKSGMVE--HVIFSVEPDDNHRKGKRLFH 201

  Fly   186 ------------AFTLAS--LAMTREEKHLPISAHVLFEIFPFCMVFGADMVVRSIGNSLMVILP 236
                        :|||:|  |...|:.|:          |||:.:.|...|::..||   :.:|.
 Worm   202 KFRNTKTTENAPSFTLSSTILVGLRDFKN----------IFPYHVCFNKQMIIEHIG---IYLLR 253

  Fly   237 E--LLGK---KITAWFDLVRPL-IAFKFQTILNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGS 295
            |  |..|   |::....||:|. |...::.:|:..|.:| :..:...::|.:||       |..|
 Worm   254 EYGLENKKTLKVSDLMQLVQPSDIQLTYKNVLSYLNTLF-IFQLKHHSKRNEVQ-------EGSS 310

  Fly   296 EP-EKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYINDLSMHDFSRDLMLAGTQQ--S 357
            |. ::.|.|||:|:.:.:...|:|:.:|.:..:..::...|||:|:.|||.:|||::....:  .
 Worm   311 EAFQQPLVLKGEMMPINDGNSIIFICSPHVTTVRDILNLKLYISDMPMHDATRDLVMLNQSRICQ 375

  Fly   358 VELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSI 422
            :||...|::..:|.||:.|.   |:.:..:||.||::.:|..:|:.||..:..  ..:.|...|:
 Worm   376 MELNKKLEETMKKMKKMTEE---LEVKKSQTDRLLFEFVPPVIAEALRAAKTV--PAQEFSDCSV 435

  Fly   423 LFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAE 487
            :|:||..|..|....:|.|:::::..::..||::.|::..|||.::.|:|::|.|.|:.:..|.|
 Worm   436 IFTDIPDFFTISVNCSPTEIITVVTDLFHRFDRIIEKHKGYKVLSLMDSYLIVGGVPNANQYHCE 500

  Fly   488 RVCDMALDMVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTS 552
            ...::||.::.....:..|...:.:|:|:|||.|.||||||..:.||:|:.|:|||....:.|.|
 Worm   501 DSLNLALGLLFEAKQVVVPKLERSVRLRIGVHCGPVVAGIVSQQKPRFCVLGNTVNVTKSICSHS 565

  Fly   553 IAMKVHISESTKVLIGPNYKII----ERGEIDVKGKGTMGTYWLEERE 596
            ...||.:|.:.:.::..:.|.|    ..|.:::: .|.:.|::||:.|
 Worm   566 SPGKVLVSNAVRTMVTKHLKSIFVFNANGYLELQ-SGKVLTHFLEKNE 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	42/157 (27%)
		HNOBA	201..404	CDD:311573	57/211 (27%)
		CYCc	383..571	CDD:214485	57/187 (30%)
		Herpes_ICP4_C	794..>955	CDD:332854
gcy-37	NP_500171.2	HNOB	3..165	CDD:285002	42/155 (27%)
		HNOBA	223..419	CDD:285003	59/219 (27%)
		CYCc	400..577	CDD:214485	57/178 (32%)
		Nucleotidyl_cyc_III	425..609	CDD:299850	54/186 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245586at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780