Protein Alignment Gyc88E and gcy-21

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_001364740.1
• Gene: gcy-21 / 191651
• WormBaseID: WBGene00001546
• Length: 1163
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 120/392 - (30%)
• Similarity: 203/392 - (51%)
• Gaps: 69/392 - (17%)

  Fly   219 GADMVVRSIGNSLMVILPELLGKKITAWFDLVRPLIAFKFQTILNRTNNIFELVTVDPVTERFDV 283
            |..:|.:|...||.::|.||.| ::..|.|  .|:...:..:::.|
 Worm   788 GVLLVQKSDVYSLAIVLYELFG-RLGPWGD--EPMEPREIVSLVKR------------------- 830

  Fly   284 QNEDLLQHEDGSEPEKSLRLKGQMVYMEN----WRMIMFLGTPVMPDLTSLITTGLYINDLSMHD 344
               :.|..:....|:.::..:...:..|.    |                   |...:|..|:|.
 Worm   831 ---EALAGKKPFRPDMAVLKESPRIVQETVVAAW-------------------TEDPLNRPSLHQ 873

  Fly   345 FSRDL--MLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMR----RTDELLYQMIPKQVADR 403
            ..|.|  :..|.:::: :...:...::.:.|||:.:...:||:.    :::.||..|:|:.|||.
 Worm   874 IKRKLKPLTIGLKRTI-MDNMVSMIEKYTDKLEKDIAERNEELEGEKAKSEALLKMMLPEVVADS 937

  Fly   404 LRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETI 468
            |:.|.|.  :.|.|::.::.|||...|.|:.:...|:::|..||.:|::||::.::..|||||||
 Worm   938 LKLGSNV--SAESFENCTVFFSDCPGFVEMSATSKPIDIVQFLNDLYTVFDRIIDQFDVYKVETI 1000

  Fly   469 GDAYMVVAGAPDKDAN-HAERVCDMALDMVDAITDLKDPSTGQHL-----RIRVGVHSGAVVAGI 527
            .|||||.:|.|..:.| ||..:..:.|.::.|:...|.    :||     |:|:|::||..|||:
 Worm  1001 ADAYMVASGLPVPNGNHHAGEIASLGLALLKAVESFKI----RHLPNEKVRLRIGMNSGPCVAGV 1061

  Fly   528 VGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIGP--NYKIIERGEIDVKGKGTMGTY 590
            |||||||||||||||||||||||..|.::::.|.:.|.::..  .|:|.|||.:::||||...||
 Worm  1062 VGLKMPRYCLFGDTVNTASRMESNGIPLRINCSGTAKEILDQLGGYEIEERGIVEMKGKGKQMTY 1126

  Fly   591 WL 592
            ::
 Worm  1127 FV 1128

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572
		HNOBA	201..404	CDD:311573	36/194 (19%)
		CYCc	383..571	CDD:214485	82/199 (41%)
		Herpes_ICP4_C	794..>955	CDD:332854
gcy-21	NP_001364740.1	Periplasmic_Binding_Protein_type1	58..422	CDD:415822
		PK_GC	612..881	CDD:270894	23/136 (17%)
		HNOBA	<890..938	CDD:400168	12/47 (26%)
		Guanylate_cyc	944..1130	CDD:306677	81/191 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810