Protein Alignment Gyc88E and gcy-6

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_001294696.1
• Gene: gcy-6 / 191644
• WormBaseID: WBGene00001533
• Length: 1086
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 160/545 - (29%)
• Similarity: 256/545 - (46%)
• Gaps: 133/545 - (24%)

  Fly   144 TMGQIREVARY-FYHKEMHIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKH------- 200
            |:.::.|...| |:..:..:|:.|......::    ::.|||:  |.|::...|...|
 Worm   562 TLSEVGETRNYLFFQIQNDVEMERVAAKKHSI----RMVFDNK--TCATMRQMRLIDHANLNKFI 620

  Fly   201 -LPISAHVLFEIFPFC-------MVFGADM---------VVRSIGNSLM---------------- 232
             :.:.|..|:.::.||       ::..|.|         :::.|.|.|.
 Worm   621 GMSLDAPQLYSVWRFCSRGSLADVIRKASMQMDGFFIYSLMKDIINGLTWIHESSHEFHGMLTSK 685

  Fly   233 -VILPELLGKKITAWFDLVRPLIAFKFQTILN------------RTNNI----------FELVTV 274
             .:|.:....|||.:     .|..|:.....|            ||::|          |.:::.
 Worm   686 NCLLNDRWQLKITDF-----GLRIFRTHDQYNKSDRLWTSPELLRTDDILGSREGDIYSFGIISA 745

  Fly   275 DPVTER--FDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYI 337
            :.:|..  ||::|    :.||..|....|:..|             |.:| .|.|..  ...:.|
 Worm   746 ELITRSSVFDLEN----RKEDAEEIIYMLKKGG-------------LQSP-RPSLEH--DESIEI 790

  Fly   338 NDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKS-----------------------KKLEESMR 379
            |...:| ..||.......:..::|....|.:..:                       .::.|.|:
 Worm   791 NPALLH-LVRDCWTERPSERPDIKQVASQLRSMNTNRNDNLMDHVFNVLESYASTLEDEVAERMK 854

  Fly   380 LLDEEMRRTDELLYQMIPKQVADRLRRGE--NPIDTCEMFDSVSILFSDIVTFTEICSRITPMEV 442
            .|.||.:::|.|||:|:|:||||:|:.|:  .|    |.||.|::.|||:|:||.:..:.||::|
 Worm   855 ELVEEKKKSDVLLYRMLPRQVADKLKLGQTVEP----ETFDIVTLFFSDVVSFTTLAGKCTPLQV 915

  Fly   443 VSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDAN-HAERVCDMALDMVDAITDLKDP 506
            |::||.:|:|||.:.|::.|||||||||.|.|.:|.|.::.| |...:..|:::.|.::.|...|
 Worm   916 VNLLNGLYTIFDGIIEQHDVYKVETIGDGYFVASGVPRRNGNEHTRNIASMSINFVKSLADFSIP 980

  Fly   507 S-TGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVL---I 567
            . .|:.::||||.|.|:||||:|||.|||||||||.|||||||||.|...::|:||....:   :
 Worm   981 HLPGEKIKIRVGFHCGSVVAGVVGLTMPRYCLFGDAVNTASRMESNSKPGQIHLSEEANQMLMRL 1045

  Fly   568 GPNYKIIERGEIDVKGKGTMGTYWL 592
            | .:....|||:.:||||.|.||||
 Worm  1046 G-GFTTEPRGEVIIKGKGVMATYWL 1069

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	4/20 (20%)
		HNOBA	201..404	CDD:311573	55/282 (20%)
		CYCc	383..571	CDD:214485	92/194 (47%)
		Herpes_ICP4_C	794..>955	CDD:332854
gcy-6	NP_001294696.1	PBP1_NPR_GC_like	29..445	CDD:107347
		ANF_receptor	57..424	CDD:279440
		PKc_like	585..822	CDD:304357	48/268 (18%)
		HNOBA	<847..879	CDD:285003	15/31 (48%)
		CYCc	858..1048	CDD:214485	92/194 (47%)
		Guanylate_cyc	885..1070	CDD:278633	90/190 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910