Protein Alignment Gyc88E and acy-2

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_504553.1
• Gene: acy-2 / 191607
• WormBaseID: WBGene00000069
• Length: 1080
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 127/540 - (23%)
• Similarity: 211/540 - (39%)
• Gaps: 163/540 - (30%)

  Fly   124 ETKQGLTLHYRS--KRRGFVYYTMGQIREVARYFYHKEMHIELVREEILFDTVHVTFQLTFDNRA 186
            |.:..|..|:||  |.|....:....:...|:.|.           |..|..|:....|..|:|.
 Worm    13 EIRSVLVKHWRSLDKARLHTIHLWLLLYAAAQIFI-----------EYYFSEVYAVLMLEADDRP 66

  Fly   187 FTLASLAMTREEKHLPISAHVLFEIFPFCM---VF-------------------GADMVVRSIGN 229
                    ..:|.|..:.     :..|||.   :|                   |..:|:.|:
 Worm    67 --------QSKENHEKVK-----KWSPFCFYASIFFIAYLILTCFAIRIRQPKEGMGLVLVSL-- 116

  Fly   230 SLMVILPELLGKKITAWFDLVRPLIAF----KFQT---------------------ILNRTNNIF 269
            ||.|:||..      :|. |..|::.|    :..|                     ||.|...||
 Worm   117 SLCVLLPAF------SWI-LHLPVVIFVSRERIHTNEHDHSALYTSLCIASVIQFFILPRHRRIF 174

  Fly   270 ELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTG 334
            .:|.|..:...|                        .::...||                   ..
 Worm   175 FVVAVSWIVANF------------------------LLIVAINW-------------------DA 196

  Fly   335 LYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRT---------DE 390
            |.:|.|.|   ...|.|...|..:.|...:....:...:.|.:.:|.:...|||         ::
 Worm   197 LNVNTLFM---CSCLSLFLHQGVIALVGVVADSNEAGNRAEIARKLTEAVYRRTELETLKDRQEQ 258

  Fly   391 LLYQMIPKQVADRL-----------------RRGENPIDTCEMF--------DSVSILFSDIVTF 430
            ||..:||..:||::                 |.|:|.....::|        |:|||||:|||.|
 Worm   259 LLLSVIPAYLADQVSKSIIQSSSTGSTVEVPRTGKNNTKNHKLFHDLHVQVHDNVSILFADIVNF 323

  Fly   431 TEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALD 495
            |.:.:::|..::|..||.:||.||:..:|....:::.:||.|..|:|.|....|||:....|.|:
 Worm   324 TVLAAQLTAKDLVRTLNELYSKFDRDAQRLQCMRIKFLGDCYYCVSGMPVNRPNHADMCVVMGLE 388

  Fly   496 MVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHIS 560
            |::.|..:: .:||..:.:|:|||:|:|:.||:||:..::.::.|.|..|:.|||..:...|||:
 Worm   389 MINTIKQVR-IATGVDVNMRIGVHTGSVLCGIMGLRKWQFDIWSDDVTLANHMESAGVPGAVHIT 452

  Fly   561 ESTKVLIGPNYKIIERGEID 580
            :|||.::..:|.|::....|
 Worm   453 KSTKDMLLGDYCIVDANTDD 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	9/41 (22%)
		HNOBA	201..404	CDD:311573	46/258 (18%)
		CYCc	383..571	CDD:214485	70/221 (32%)
		Herpes_ICP4_C	794..>955	CDD:332854
acy-2	NP_504553.1	CYCc	253..463	CDD:214485	67/210 (32%)
		Guanylate_cyc	308..459	CDD:278633	57/151 (38%)
		CYCc	817..1034	CDD:214485
		Guanylate_cyc	840..1054	CDD:278633

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810