Protein Alignment Gyc88E and daf-11

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: NP_505960.3
• Gene: daf-11 / 179605
• WormBaseID: WBGene00000907
• Length: 1077
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 161/545 - (29%)
• Similarity: 243/545 - (44%)
• Gaps: 148/545 - (27%)

  Fly    90 GRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLTL-------HYRSKRRGF------- 140
            |..:||.|.||:.:|            .|.|   :....|||       |:..|..||
 Worm   505 GLFLRDILKGLEYIH------------ASAI---DFHGNLTLHNCMLDSHWIVKLSGFGVNRLLV 554

  Fly   141 VYYTMGQIREVARYFYHKEMHIELVREEIL--FDTVHVTFQLTFDNRAFTLASLAMTREEKHLPI 203
            .:.|.|||        ..|.|..:::.|.|  ||.   ..:..:.|.|        .|.|:.|
 Worm   555 KWKTSGQI--------FTEDHTPVIKSEELHYFDP---AMKKIWKNYA--------DRNERAL-- 598

  Fly   204 SAHVLFEIFPFCMVFGADMVVRSIGNSLMVILPELLGKK--ITAWFDLVRP-----LIAFKFQTI 261
                   |.|   .||....:.|.|    |||.|::.||  :...||..|.     ||..:...|
 Worm   599 -------ITP---QFGKKCDMYSFG----VILHEIILKKKFVEQLFDSPREEDDSVLIDDENDAI 649

  Fly   262 LNRTNNIFELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPD 326
            .:|    |.|..:.|  |..::.| ||::                  .:||     ..|: |.||
 Worm   650 ASR----FPLPIIIP--EGIEMHN-DLIK------------------MLEN-----CFGS-VRPD 683

  Fly   327 LT---SLITTGLYINDLSMHDFSRDLML-------AGTQQSVELKLA-LDQEQQKSKKLEESMRL 380
            :.   .:|.|     .|.|.....|||:       .|..::|:.:.| |::||:|.
 Worm   684 IALARKIIDT-----VLKMSGSLVDLMIKNLTAYTQGLNETVKNRTAELEKEQEKG--------- 734

  Fly   381 LDEEMRRTDELLYQMIPKQVADRLRRGENPIDTCEMFDSVSILFSDIVTFTEICSRITPMEVVSM 445
                    |:||.:::||.||:.|:.| ..:|. :::::.:||:||||.||.:||:..|||||::
 Worm   735 --------DQLLMELLPKSVANDLKNG-IAVDP-KVYENATILYSDIVGFTSLCSQSQPMEVVTL 789

  Fly   446 LNAMYSIFDKLTERNSVYKVETIGDAYMVVAGAP---DKDANHAERVCDMALDMVDAITDLKDP- 506
            |:.||..||.:..:...||:|||||||.|.||.|   :||  |.:.:|.:||...|.:...:.|
 Worm   790 LSGMYQRFDLIISQQGGYKMETIGDAYCVAAGLPVVMEKD--HVKSICMIALLQRDCLHHFEIPH 852

  Fly   507 STGQHLRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIG--- 568
            ..|..|..|.|.:||.|.||::|.|.|||..||:.|..||:|||:.:..::.::.:::.|:.
 Worm   853 RPGTFLNCRWGFNSGPVFAGVIGQKAPRYACFGEAVILASKMESSGVEDRIQMTLASQQLLEENF 917

  Fly   569 PNYKIIERGEIDVKGKGTMGTYWLE 593
            |.:....||...::|.|.:.|||||
 Worm   918 PQFVCSNRGGRTIEGIGRILTYWLE 942

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	22/87 (25%)
		HNOBA	201..404	CDD:311573	54/220 (25%)
		CYCc	383..571	CDD:214485	75/194 (39%)
		Herpes_ICP4_C	794..>955	CDD:332854
daf-11	NP_505960.3	Periplasmic_Binding_Protein_Type_1	<33..295	CDD:299141
		PKc_like	447..695	CDD:304357	65/275 (24%)
		HNOBA	<714..750	CDD:285003	14/52 (27%)
		CYCc	729..922	CDD:214485	78/213 (37%)
		Guanylate_cyc	756..943	CDD:278633	75/190 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810