Protein Alignment Gyc88E and LOC1274705

DIOPT Version :10

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: XP_313866.5
• Gene: LOC1274705 / 1274705
• VectorBaseID: AGAMI1_000741
• Length: 649
• Species: Anopheles gambiae
• Alignment Length: 651
• Identity: 232/651 - (35%)
• Similarity: 356/651 - (54%)
• Gaps: 67/651 - (10%)

  Fly     1 MYGLLLENLSEYIKSVYGEEKWEDIRRQAGIDSPSFSVHQVYPENLLQKLAKKAQQVLGVSERDF 65
            |||:|||::..:::..|||..|.......|..:..|:.||:||:||:..||.....:.|....:|
Mosquito     1 MYGMLLESVQHFVQLEYGEFVWRQALLTTGCKNTVFNTHQLYPDNLIPDLAAALSAITGKPFDEF 65

  Fly    66 MDQMGVYFVGFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPRMRAPSFICENETKQGLT 130
            |...|..||.|...:|||.::...||:..|||:.:||:|..::|:|.:|::||.......:.|..
Mosquito    66 MIFFGRCFVRFFSNFGYDELIKATGRYFCDFLHSVDNIHLQMRFTYRKMKSPSMQLTEVDENGAV 130

  Fly   131 LHYRSKRRGFVYYTMGQIREVARYFYHKEMHIELVREE----------IL----FDTVHVTFQLT 181
            |.|||.|.||..|..||:.|:|:..|..::.|:::..:          |.    ..||.|.::|.
Mosquito   131 LVYRSTRTGFSKYLRGQLLEIAKQLYGMDVSIKVLESQNDTPGGTSGPIAPQGGLKTVIVKYRLD 195

  Fly   182 FDNRAFTLASLAMTREEKHL---PISAHVLFEIFPFCMVFGADMVVRSIGNSLMVIL-------- 235
            ||||.:....:.:......|   |:::.:|..:|||.::...:|.:.::|..|:...
Mosquito   196 FDNREYMQRRVHIKAHPSQLQLTPVNSKLLLNLFPFALILNEEMKITAVGEKLIESWMLNNVNRS 260

  Fly   236 -PELLGKKITAWFDLVRPL-IAFKFQTILNRTNNIFEL---------------VTVDPVTERFDV 283
             .||||.|:|..|.|.||. |.|.::.|......:||:               ..||..|....|
Mosquito   261 PTELLGAKVTDHFKLRRPSGITFTWENIKRLQTVLFEIQLLKGSSAKGTKDESKIVDTKTSLSQV 325

  Fly   284 QNEDLLQHED-----------GSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITTGLYI 337
            ....  ..||           ||:..:|:.|||:|.|:::...::||.:|::.:|..|...|||:
Mosquito   326 DTSS--STEDAAKIMTSIPRRGSQGLRSILLKGEMRYIKDINSLVFLCSPLINNLEELREMGLYL 388

  Fly   338 NDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPKQVAD 402
            |||:.|..||:::.:|......|.|..::|:|::::||.|:.|.|...|:.|||||.|||:.:|:
Mosquito   389 NDLNPHGLSREMVFSGFSHYSRLDLMCEREEQRAEELETSLALADSWKRQGDELLYSMIPRSIAE 453

  Fly   403 RLRRGENPIDTCEMFDSVSILFSDI-VTFTEICSRITPMEVVSMLNAMYSIFDKLTERNSVYKVE 466
            |||.|:||.:||:.|:.|::||::: .|.|...|....|..|:.|||.:|.||:|......||||
Mosquito   454 RLREGQNPHETCQSFEEVTVLFAEVQETITGDDSIKYAMTTVNTLNAAFSAFDELIHSPMAYKVE 518

  Fly   467 TIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPSTGQHLRIRVGVHSGAVVAGIVGLK 531
            |:|..||.|:||||.:..||:.:.|:||||:.:|..|..|..|    :::|.|||.:||||||||
Mosquito   519 TVGKVYMAVSGAPDINPFHAQHMADLALDMLHSIRQLNLPGVG----VKIGFHSGPIVAGIVGLK 579

  Fly   532 MPRYCLFGDTVNTASRMESTS----IAMKVHISESTKVLIGPNYKIIERGEIDVKGKGTMGTYWL 592
            :||||||||||||||||||:.    |.:..:.::..|.|   .|.:..||::.|||||.|.|:||
Mosquito   580 VPRYCLFGDTVNTASRMESSGETDCIQVSGYTAQKLKKL---GYVLAYRGKVAVKGKGDMETFWL 641

  Fly   593 E 593
            :
Mosquito   642 Q 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..163	CDD:462233	56/160 (35%)
		HNOBA	201..404	CDD:462234	72/241 (30%)
		CYCc	383..571	CDD:214485	91/192 (47%)
		PHA03307	794..>955	CDD:223039
LOC1274705	XP_313866.5	HNOB	2..164	CDD:462233	57/161 (35%)
		HNOBA	219..455	CDD:462234	71/237 (30%)
		Guanylate_cyc	466..643	CDD:425528	85/184 (46%)