Protein Alignment Gyc88E and Adcy7

DIOPT Version :9

• Sequence 1: NP_001036711.1
• Gene: Gyc88E / 41825
• FlyBaseID: FBgn0038295
• Length: 1097
• Species: Drosophila melanogaster
• Sequence 2: XP_006530643.1
• Gene: Adcy7 / 11513
• MGIID: 102891
• Length: 1146
• Species: Mus musculus
• Alignment Length: 553
• Identity: 128/553 - (23%)
• Similarity: 234/553 - (42%)
• Gaps: 144/553 - (26%)

  Fly   161 HIELVREEILFDTVHVTFQLTFDNRAFTLASLAMTREEKHLPISAHVLFEIFPFCMV-------- 217
            |.:|.|.:::..|            ||.:.:|.         ::.:||  ::..|:|
Mouse    56 HEDLRRHQVVLGT------------AFLMLTLF---------VALYVL--VYVECLVQRWLRALA 97

  Fly   218 ---FGADMVVRSIGNSLMVILPELLGKKITAW----FDLVRPLIAFKFQTILNR-------TNNI 268
               :...||:.|      |::.:.|..:..||    |.|....:.:....:..|       |:.:
Mouse    98 LLTWACLMVLGS------VLMWDSLENEAHAWEQVPFFLFVVFVVYALLPLSRRAAIVAGVTSTV 156

  Fly   269 FELVTVDPVTERFDVQNEDLLQHEDGSEPEKSLRLKGQMVYMENWRMIMFLGTPVMPDLTSLITT 333
            ..|:....||..|....         |..:..|:|....|       |:..|.          .|
Mouse   157 SHLLVFGAVTRAFQTSM---------SSTQLGLQLLANAV-------ILLGGN----------FT 195

  Fly   334 GLYINDLSMHDFSRDLMLAGTQQSVELKLALDQEQQKSKKLEESMRLLDEEMRRTDELLYQMIPK 398
            |.: :...:.|.||||.:. |.:.::::                 |.|..|.|:.:.||..::|.
Mouse   196 GAF-HKHQLQDASRDLFIY-TVKCIQIR-----------------RKLRVEKRQQENLLLSVLPA 241

  Fly   399 QVA--------DRLRRG-------ENPIDT--CEMFDSVSILFSDIVTFTEICSRITPMEVVSML 446
            .::        :||:.|       :|...:  .:...:||||::|||.||.:.|..:|.|:|.:|
Mouse   242 HISMGMKLAIIERLKEGGDRHYMPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVVL 306

  Fly   447 NAMYSIFDKLTERNSVYKVETIGDAYMVVAGAPDKDANHAERVCDMALDMVDAITDLKDPSTGQH 511
            |.::..||::.:.|...:::.:||.|..|:|.|.....||.....|.||:.:||..::: :||..
Mouse   307 NELFGKFDQIAKANECMRIKILGDCYYCVSGLPVSLPTHARNCVKMGLDICEAIKQVRE-ATGVD 370

  Fly   512 LRIRVGVHSGAVVAGIVGLKMPRYCLFGDTVNTASRMESTSIAMKVHISESTKVLIGPNYKIIER 576
            :.:|||:|||.|:.|::||:..:|.::...|:.|:|||:..:..:|||:|:|...:...|::.:
Mouse   371 ISMRVGIHSGNVLCGVIGLRKWQYDVWSHDVSLANRMEAAGVPGRVHITEATLNHLDKAYEVED- 434

  Fly   577 GEIDVKGKGTMGTYWLEERENRLPLQLTAALQVHPLSPVPPTPTPKTKAIMPPVSKP---LTPMM 638
                  |.|.....:|:|      :.:...|.:.|.|..||.|:..       :|||   .|..|
Mouse   435 ------GHGEQRDPYLKE------MNIRTYLVIDPRSQQPPPPSHH-------LSKPKGDATLKM 480

  Fly   639 PVSV-------SLAASMPTSNVPAVDVMASSSS 664
            ..||       |..|:.|.:::...:.::||.:
Mouse   481 RASVRVTRYLESWGAARPFAHLNHRESVSSSET 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc88E	NP_001036711.1	HNOB	2..164	CDD:311572	1/2 (50%)
		HNOBA	201..404	CDD:311573	40/232 (17%)
		CYCc	383..571	CDD:214485	63/204 (31%)
		Herpes_ICP4_C	794..>955	CDD:332854
Adcy7	XP_006530643.1	AC_N	<75..251	CDD:318454	41/237 (17%)
		Guanylate_cyc	272..422	CDD:306677	53/150 (35%)
		DUF1053	487..593	CDD:399378	5/27 (19%)
		Guanylate_cyc	890..1085	CDD:306677

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810