DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlyS and ALG1

DIOPT Version :9

Sequence 1:	NP_731967.2	Gene:	GlyS / 41823	FlyBaseID:	FBgn0266064	Length:	709	Species:	Drosophila melanogaster
Sequence 2:	NP_061982.3	Gene:	ALG1 / 56052	HGNCID:	18294	Length:	464	Species:	Homo sapiens

Alignment Length:	173	Identity:	37/173 - (21%)
Similarity:	62/173 - (35%)	Gaps:	46/173 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   554 GIPSVTTNLSGF-GCFM-EEHISDPKSYGIYIVDRRYIGLENSVQQLSSFMME-FSRLNRRQRII 615
            |:||:.  :..| ||.. .:.:.|..:||..|:...: |..:.:..|:.:..: |.||:.....:
Human   134 GLPSIA--VCWFVGCLCGSKLVIDWHNYGYSIMGLVH-GPNHPLVLLAKWYEKFFGRLSHLNLCV 195

  Fly   616 QRNRTERLSDLLDWRTLGIYYRQARVKALQAVYPDYVDELSL---------YGSKNNLIFSRPHS 671
            .....|.|:|....|.:.:|.:.|          .:..|..|         .||.::..  |..|
Human   196 TNAMREDLADNWHIRAVTVYDKPA----------SFFKETPLDLQHRLFMKLGSMHSPF--RARS 248

  Fly   672 EPPSPTSSR----------------HTTPA---PSVHGSDDED 695
            ||..|.:.|                ...||   .|...::|||
Human   249 EPEDPVTERSAFTERDAGSGLVTRLRERPALLVSSTSWTEDED 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyS	NP_731967.2	Glycogen_syn	53..697	CDD:399009	37/173 (21%)
ALG1	NP_061982.3	PLN02275	27..424	CDD:215155	37/173 (21%)
		GT1_ALG1_like	30..461	CDD:99986	37/173 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..262		6/20 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900