DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GlyS and Piga

DIOPT Version :9

Sequence 1:	NP_731967.2	Gene:	GlyS / 41823	FlyBaseID:	FBgn0266064	Length:	709	Species:	Drosophila melanogaster
Sequence 2:	NP_035211.2	Gene:	Piga / 18700	MGIID:	99461	Length:	485	Species:	Mus musculus

Alignment Length:	407	Identity:	82/407 - (20%)
Similarity:	136/407 - (33%)	Gaps:	122/407 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   244 LCAGNTDFYNNLDKFAVDEEAGKRQIYH-RYCL-ERGATHLAHVFTTVSEITGYEAEHLLKRKPD 306
            :|..:..||.|:.       ..:..||. ..|| |||     |...||:...|       .||..
Mouse    35 ICMVSDFFYPNMG-------GVESHIYQLSQCLIERG-----HKVITVTHAYG-------NRKGV 80

  Fly   307 IITPNGLNV------------------------------KKFSAIHEFQNLHAVAKEKI------ 335
            ....|||.|                              ::.:.||...:..|:|.:.:
Mouse    81 RYLTNGLKVYYLPLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSSFSAMAHDALFHAKTM 145

  Fly   336 ---NEFVRGHFYGHIDFD---LDKTLYFFIAGRYEFGNKGADIFIEALARLNAMLKHE-KPD-TT 392
               ..|.....:|..|..   .:|.|...:......      |.:...::.|.:|:.. .|: .:
Mouse   146 GLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHI------ICVSYTSKENTVLRAALNPEIVS 204

  Fly   393 VVAFLIFPTKTNNFNVDSLRGH-AVIKQLRDTINNVQQAVGKRMFDTCLQGNIPNADDLLQKDDL 456
            |:...:.||   :|..|..|.| :||     |:..|.:.|.::..| .|.|.||   :|.|
Mouse   205 VIPNAVDPT---DFTPDPFRRHDSVI-----TVVVVSRLVYRKGTD-LLSGIIP---ELCQ---- 253

  Fly   457 VKIKRCMFAMQRDSMPPVTTHNVADDWNDPVLSSIRRCHLFNSRHDRVKMVFHPEFLTSTNPLFG 521
             |.:...|.:..:....:            :|..:|..:   ..||||:::...|.....|.|
Mouse   254 -KYQELHFLIGGEGPKRI------------ILEEVRERY---QLHDRVQLLGALEHKDVRNVL-- 300

  Fly   522 IDYEEFVRGCHLGVFPSYYEPWGYTPAECTVMGIPSVTTNLSGFGCFMEEH---ISDPKSYGIYI 583
                  |:| |:.:..|..|.:.....|....|:..|:|.:.|....:.|.   :.:|.
Mouse   301 ------VQG-HIFLNTSLTEAFCMAIVEAASCGLQVVSTKVGGIPEVLPESLIILCEPS------ 352

  Fly   584 VDRRYIGLENSVQQLSS 600
            |.....|||.::.|:.|
Mouse   353 VKSLCDGLEKAIFQVKS 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GlyS	NP_731967.2	Glycogen_syn	53..697	CDD:399009	82/407 (20%)
Piga	NP_035211.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
Piga	NP_035211.2	GT4_PIG-A-like	34..433	CDD:340827	82/407 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0438
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900