Protein Alignment CG6966 and Fem-1

DIOPT Version :10

• Sequence 1: NP_001097796.1
• Gene: CG6966 / 41816
• FlyBaseID: FBgn0038286
• Length: 664
• Species: Drosophila melanogaster
• Sequence 2: NP_611508.1
• Gene: Fem-1 / 37344
• FlyBaseID: FBgn0034542
• Length: 702
• Species: Drosophila melanogaster
• Alignment Length: 693
• Identity: 219/693 - (31%)
• Similarity: 335/693 - (48%)
• Gaps: 98/693 - (14%)

  Fly    14 NNLAQLKATLYNKSSVEVGSLISAK------VN---------GATPLVISCRNGHYDIVEYLLTK 63
            |||.....:....|.||:.:.:|.:      ||         ..|||.::...|:...|:.||:.
  Fly    59 NNLHLAARSGQMLSFVEILNSVSCRAVQTHLVNTNFDQPDGQSLTPLTMAAMMGNVKFVKTLLSH 123

  Fly    64 CRANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGH 128
            ...::::..:|.:||..:..|..||.||..|||.||||||:.||.:|..|:..|:||||||::|.
  Fly   124 YDVDLDRECNVIYDGMVVYGATALWVAAGMGHLQIVKMLVQAGAAINHNTKAQSSPLRAACYEGR 188

  Fly   129 YEIVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTALHDCAESG 193
            .:||::|:.:|||....|...:..||||.||||..:.:.||...:..|..::.|.||||..||||
  Fly   189 LDIVEFLIDNGADVNATNLFNNNTLMIAAYKGHHLVVKTLLQNGSRANDQALCGATALHYAAESG 253

  Fly   194 SLQILQLLLKHGATMDVDYYGMTPLLAASVTGHMPIVEHLITLP-CVSRESRIHALELLGATYVD 257
            .|.::..||.||||:..:..|:||.|.|:...|..::|..|..| .:|.|.:|.|||||||||.:
  Fly   254 HLDVVVALLDHGATLKKNELGITPALQAAERLHEDVLEAFIERPELMSLEEQITALELLGATYAN 318

  Fly   258 R--KRDMAAALNLWRRALEERAVEP--PLEKKVQEPVPAYEMVREVTSVEELEEMVLDPDEMRMQ 318
            .  |.|:..|.....||::.|...|  .:.|:||..||||:...|..::.||..:.|:...:.|:
  Fly   319 DKIKYDVNKAYGYLLRAMQLRYSNPRGVIRKRVQPTVPAYDNWLETENLPELYAIKLNHHSIHME 383

  Fly   319 ALVIRQRILGPTHPDTSYYIRFRGAHYADAGRFDRCIELWSYALTMQQKILQPLSPMTQSSLLSF 383
            :|.||:||||..:|:....|.:|||..||.|||.:|..||:||:.::.:    .:......||.|
  Fly   384 SLAIRERILGRNNPELPQAIIYRGAVMADQGRFYQCQVLWNYAIDLRMR----NNVSVDRDLLRF 444

  Fly   384 AELFSFML-VEAGRLLPRGRVVPPIEPDSMLTIFYKAVKEVERGLAFTLEQQKDQQHPQKQLPAA 447
            |:||:.:| ||...|          ..|.:|.:..|..:|:|.. .|.:::.|....|  .|...
  Fly   445 AQLFAQILRVENHNL----------TLDHVLPVLAKCQQEIENN-KFKIKEAKPNACP--SLWQD 496

  Fly   448 DKSPSCSASSSASSSSSTTLLSAHQHDCNHDPNALSRTMISAIHIGCLLSSLLDTDALSPEMRRQ 512
            ..:.:|  .::.......|.|:..:.|.|.|...:.:..:       ::...:..|
  Fly   497 QNNQNC--ITALYLIKIVTHLARRKKDQNIDEEHIQQLFL-------VVRKFIQND--------- 543

  Fly   513 VMGALYRLNRLKVRVRFDRTALHYACYREGTLAGRYP--------SCQFPSVTLAKALLEVGADP 569
                        .|::..:|.||.|      :.|..|        .|:||....|..|:..||..
  Fly   544 ------------TRLQDGQTLLHIA------VNGVMPVDEFYTNEMCRFPCYATALVLVHCGASV 590

  Fly   570 NAIDEAGNTPLHLA-----TMQPYVEPLSHIL---LEGGAHLDTKNYAGETFES-----LLAPTP 621
            .|:|...|||||:.     |.|.....::.||   :|.|||||..|.||:|..:     :|| ..
  Fly   591 VAVDSDRNTPLHILVTKVNTTQDRQAEMARILELFVEAGAHLDAVNAAGQTAATACKLPILA-NR 654

  Fly   622 MHKIIDPMKYTTLACLAARTIKKHDIRYEGTVPATLYEFIELH 664
            :|  .....:|:|.|||||:|..:.:.::|.:|..|..||::|
  Fly   655 LH--AHQNAHTSLKCLAARSIATNRLNFKGLIPTQLEAFIQMH 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6966	NP_001097796.1	ANKYR	2..236	CDD:440430	87/236 (37%)
		ANK repeat	40..72	CDD:293786	8/40 (20%)
		ANK repeat	86..113	CDD:293786	16/26 (62%)
		ANK repeat	118..146	CDD:293786	13/27 (48%)
		ANK repeat	148..179	CDD:293786	11/30 (37%)
		ANK repeat	181..210	CDD:293786	16/28 (57%)
		ANKYR	<525..>612	CDD:440430	34/102 (33%)
		ANK repeat	529..573	CDD:293786	14/51 (27%)
		ANK repeat	575..607	CDD:293786	15/39 (38%)
Fem-1	NP_611508.1	ANKYR	89..335	CDD:440430	96/245 (39%)
		ANK repeat	103..129	CDD:293786	7/25 (28%)
		ANK repeat	142..173	CDD:293786	17/30 (57%)
		ANK repeat	178..206	CDD:293786	13/27 (48%)
		ANK repeat	208..239	CDD:293786	11/30 (37%)
		ANK repeat	241..266	CDD:293786	13/24 (54%)
		ANKYR	447..>642	CDD:440430	56/243 (23%)
		ANK repeat	548..594	CDD:293786	14/51 (27%)
		ANK repeat	596..636	CDD:293786	15/39 (38%)