DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6966 and LOC110440003

DIOPT Version :9

Sequence 1:	NP_001097796.1	Gene:	CG6966 / 41816	FlyBaseID:	FBgn0038286	Length:	664	Species:	Drosophila melanogaster
Sequence 2:	XP_021334017.1	Gene:	LOC110440003 / 110440003	-ID:	-	Length:	289	Species:	Danio rerio

Alignment Length:	262	Identity:	133/262 - (50%)
Similarity:	162/262 - (61%)	Gaps:	23/262 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDYKFIVFNAARDNNLAQLKATLYNKSSVEVGSLISAKVNGATPLVISCRNGHYDIVEYLLTKCR 65
            ||....|||||||..|..::..|.|||..|..:|...:..|.|||:|:.|.||..:|.:||.:|.
Zfish     1 MDISAAVFNAARDGKLKLMQKLLINKSPEERAALAEERTEGGTPLLIAARYGHLPVVHFLLERCG 65

  Fly    66 ANVEQVGSVSFDGEPIEDAPPLWCAAAAGHLGIVKMLVRRGANVNSTTRTNSTPLRAACFDGHYE 130
            ||||..|||:||||.||.|||||.|:|||||.:||.|:..||:||:||.||||||||||||||.|
Zfish    66 ANVELGGSVNFDGETIEGAPPLWAASAAGHLPVVKALLEHGASVNNTTLTNSTPLRAACFDGHLE 130

  Fly   131 IVKYLVHHGADFEVANRHGHTCLMIACYKGHFRIAQYLLSLNADVNRCSVKGNTAL-----HDCA 190
            ||:|||.|.||.|||||||||||||:|||||..|||:||...|||||.||||...|     :.|
Zfish   131 IVRYLVEHQADLEVANRHGHTCLMISCYKGHREIAQFLLEKGADVNRRSVKGGVLLLSLIIYTC- 194

  Fly   191 ESGSLQILQLLLKHGATMDVDYYGMTPLLA--ASVTGH--MPIVEHLITLPCVSRESRIHALELL 251
                    :|:..|..|     :..||..:  ||.:.|  :.|..||.|..|....:.:|..:.:
Zfish   195 --------KLITAHLQT-----HHCTPASSSPASTSLHTCILITAHLQTHHCTPASTSLHTCKHI 246

  Fly   252 GA 253
            .|
Zfish   247 TA 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6966	NP_001097796.1	Ank_2	10..112	CDD:289560	54/101 (53%)
		ANK	40..169	CDD:238125	89/128 (70%)
		ANK repeat	40..72	CDD:293786	16/31 (52%)
		ANK repeat	86..113	CDD:293786	16/26 (62%)
		Ank_2	87..177	CDD:289560	66/89 (74%)
		ANK	110..234	CDD:238125	70/132 (53%)
		ANK repeat	118..146	CDD:293786	22/27 (81%)
		ANK repeat	148..179	CDD:293786	23/30 (77%)
		ANK repeat	181..210	CDD:293786	7/33 (21%)
		Ank_4	182..234	CDD:290365	13/60 (22%)
		ANK	528..>612	CDD:238125
		ANK repeat	529..573	CDD:293786
		ANK repeat	575..607	CDD:293786
LOC110440003	XP_021334017.1	Ank_2	<6..68	CDD:330894	27/61 (44%)
		ANK	40..169	CDD:238125	89/128 (70%)
		ANK repeat	40..75	CDD:293786	18/34 (53%)
		ANK repeat	82..113	CDD:293786	19/30 (63%)
		ANK repeat	115..146	CDD:293786	25/30 (83%)
		ANK repeat	148..178	CDD:293786	22/29 (76%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D133963at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010