Protein Alignment CG6974 and NRP2

DIOPT Version :10

• Sequence 1: NP_650414.1
• Gene: CG6974 / 41815
• FlyBaseID: FBgn0038285
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: NP_957718.1
• Gene: NRP2 / 8828
• HGNCID: 8005
• Length: 931
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 47/257 - (18%)
• Similarity: 94/257 - (36%)
• Gaps: 67/257 - (26%)

  Fly    25 IESYENYYNEIHIDDEQAEA-----KTRNALTSPLQRWPGNKILYRISTDYSEQEVA-NVRTAMS 83
            ||.::..|:.|.|.|..:|:     |....:..|.....|:.:..:.::||:.|... ::|..:.
Human    78 IEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142

  Fly    84 SFGEQTCVQFEEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAV---- 144
            ..|.:.|            .|.:.    |||......|: |..: ||.:......|..|.:
Human   143 KTGSEDC------------SKNFT----SPNGTIESPGF-PEKY-PHNLDCTFTILAKPKMEIIL 189

  Fly   145 ------IQHETLHLLGLFHEQSRPDRD-EYVQID-YDNIPR------KYWSQFMAMD-QTTTFNV 194
                  ::|:.|.:         .:.| :|..:| :|.||.      ||.......: :::|..:
Human   190 QFLIFDLEHDPLQV---------GEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245

  Fly   195 PYDYESVMHYSKNAFA-------KDP------SKPTIRALIGGKAVEREMGQVRGPSEGDWT 243
            ...:.:.|..:|:.|:       ::|      :.|.  .:..|:....::......|:|.||
Human   246 SLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPL--GMESGRIANEQISASSTYSDGRWT 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	38/218 (17%)
NRP2	NP_957718.1	CUB	28..141	CDD:238001	14/62 (23%)
		CUB	149..265	CDD:238001	25/142 (18%)
		FA58C	280..426	CDD:238014	6/28 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	298..317		4/8 (50%)
		FA58C	438..591	CDD:238014
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	601..622
		MAM	641..794	CDD:214533
		DUF3481	850..931	CDD:403259