DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and bmp1b

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_005155463.1	Gene:	bmp1b / 559877	ZFINID:	ZDB-GENE-060818-2	Length:	970	Species:	Danio rerio

Alignment Length:	216	Identity:	66/216 - (30%)
Similarity:	108/216 - (50%)	Gaps:	14/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    41 QAEAKTRNALTS-PLQRWPGNKILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEE--IEGAPPA 102
            |:..:.|.|.|: |.:.||...|.|.||.:::..:.|..:.||..:.:.|||.|.|  :|
Zfish    96 QSILRRRRAATARPERVWPNGIIPYIISGNFTGSQRAIFKQAMRHWEKHTCVTFVERSVE----- 155

  Fly   103 GKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDEY 167
             :.|:.|...|..|.:.||.:  ..||..:.:.:.|... .::.||..|::|.:||.:||||||:
Zfish   156 -ESYIVFTLRPCGCCSFVGRR--GGGPQAISIGKNCDKF-GIVVHELGHVIGFWHEHTRPDRDEH 216

  Fly   168 VQIDYDNIPRKYWSQFMAM--DQTTTFNVPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVERE 230
            |.|..:||.......|:.|  |...:....||::|:|||::|.|::.....|:........|...
Zfish   217 VDIFRENIQPGQEYNFIKMEPDDVDSLGEVYDFDSIMHYARNTFSRGIYLDTMLPKYDVDGVRPP 281

  Fly   231 MGQVRGPSEGDWTKIRLMYKC 251
            :||....|:||..:.|.:|:|
Zfish   282 IGQRTRLSKGDIAQARKLYRC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	60/199 (30%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	57/193 (30%)
bmp1b	XP_005155463.1	ZnMc_BMP1_TLD	109..303	CDD:239808	62/203 (31%)
		Astacin	111..303	CDD:279708	61/201 (30%)
		CUB	305..414	CDD:278839
		CUB	418..527	CDD:278839
		EGF_CA	530..570	CDD:214542
		CUB	575..684	CDD:278839
		FXa_inhibition	691..726	CDD:291342
		CUB	731..840	CDD:278839
		CUB	844..957	CDD:278839
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810