DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6974 and cuzd1.2

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_021323075.1	Gene:	cuzd1.2 / 555768	ZFINID:	ZDB-GENE-131119-30	Length:	718	Species:	Danio rerio

Alignment Length:	256	Identity:	55/256 - (21%)
Similarity:	85/256 - (33%)	Gaps:	74/256 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 FLKAVRYLLL------AGI-------FAPNLVASEG-------------IESYENYY----NEIH 36
            |....|||.:      :|:       |..:|.|.:|             ..||.|..    |:::
Zfish   411 FHSTSRYLTVVFRSDFSGVSHGFKAHFTSSLTADQGRVDCSSDNMVIVLRRSYLNSLGFSGNDLY 475

  Fly    37 IDDEQAEAKTRNALTSPLQRWPGN-----KILYRISTDYSEQEVANVRTAMSSFG---------- 86
            :||........:  |..:.|:|.|     |.:......|:.    |||.:.|..|
Zfish   476 VDDRLCRPNISS--TEVVFRFPLNTCGTAKKMMNSFVSYTN----NVRASPSQSGVITRQSEFLL 534

  Fly    87 -------EQTCVQF----EEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLT 140
                   ..|.||.    |||......|..  .|..|.....:|...|.:...|:||.||:....
Zfish   535 SVGCRMEPDTIVQIFYKAEEIPNGNITGTG--RFNASIAFYTSRKFNQQIYDSPYEVYLNDDLFV 597

  Fly   141 MPAVIQHETLHLLGLFHEQ--SRPDRDEYVQIDYD----NIPR--KYWSQFMAMDQTTTFN 193
            ...:.:.:.  .|.||.|.  :.|:.:::....||    ..||  .:.|....:||...|:
Zfish   598 QVKLTRFDA--SLDLFLETCVASPNPNDFKDYSYDLLRNGCPRDSTFQSYINGVDQYAQFS 656

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	39/173 (23%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	37/169 (22%)
cuzd1.2	XP_021323075.1	CUB	21..127	CDD:238001
		Somatomedin_B	131..164	CDD:307259
		Somatomedin_B	175..214	CDD:321959
		Somatomedin_B	<239..260	CDD:307259
		CUB	330..439	CDD:238001	6/27 (22%)
		ZP	450..694	CDD:214579	46/217 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900