DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6974 and tll2l

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_001016661.1	Gene:	tll2l / 549415	XenbaseID:	XB-GENE-478930	Length:	500	Species:	Xenopus tropicalis

Alignment Length:	246	Identity:	74/246 - (30%)
Similarity:	118/246 - (47%)	Gaps:	26/246 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 AGIFAPNLVASEGIESYENYYNEIHIDDEQAEAKTRNALTSPLQRWPGNK-----ILYRISTDYS 71
            |.||...:.::|||:       ::.:..:.|....|::|.....:|..:.     :.:.:|..|:
Frog    43 ADIFTQIIASNEGID-------QLLLQGDIAIRVVRSSLQCDNCKWDISSNGKVPVPFTVSPGYT 100

  Fly    72 EQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLNE 136
            :.::|.:..||..|...|||.|     .|...::.|....:.|.|.:.:|   .|.|..:|.|::
Frog   101 KSQLALITAAMQEFETLTCVDF-----VPKTNEKNVININNGNGCWSYIG---RSGGVQQVSLSK 157

  Fly   137 KCLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDNI-PRKYWSQFMAMDQTTTFNVPYDYES 200
            :...:..:||||..|:||..||..|.|||:||.:...|| |....:..:|:  |....:||||.|
Frog   158 QSCMVKGIIQHELNHVLGFVHEHVRSDRDQYVNVVKKNILPDSLGNFDIAV--TNNLGLPYDYYS 220

  Fly   201 VMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
            ||||.:|||:..|..||   ||.......::||..|.:..|..||..:|.|
Frog   221 VMHYPRNAFSISPFLPT---LITKPDPTIQIGQRYGLTNLDIAKINKLYNC 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	64/201 (32%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	62/195 (32%)
tll2l	NP_001016661.1	ZnMc_hatching_enzyme	86..268	CDD:239810	63/194 (32%)
		CUB	272..382	CDD:238001
		CUB	385..495	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020