Protein Alignment CG6974 and MEP1A

DIOPT Version :10

• Sequence 1: NP_650414.1
• Gene: CG6974 / 41815
• FlyBaseID: FBgn0038285
• Length: 251
• Species: Drosophila melanogaster
• Sequence 2: XP_011512930.1
• Gene: MEP1A / 4224
• HGNCID: 7015
• Length: 774
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 74/211 - (35%)
• Similarity: 102/211 - (48%)
• Gaps: 18/211 - (8%)

  Fly    45 KTRNALTSPLQRW--PGNKILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGKRYV 107
            |:||.|..|..||  |   |.|.::.:........:..|...|..::||.|:..||.    ..|:
Human    91 KSRNGLRDPNTRWTFP---IPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEGE----SSYI 148

  Fly   108 SFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDY 172
            .|::... |.:.||.|.:.   ..:.:.:.| ...|:|:||.||.||.:|||||.|||:||.|.:
Human   149 IFQQFDG-CWSEVGDQHVG---QNISIGQGC-AYKAIIEHEILHALGFYHEQSRTDRDDYVNIWW 208

  Fly   173 DNIPRKYWSQFMAMDQT--TTFNVPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVR 235
            |.|...|...|...|.:  |..|.||||||:|||...:|.|:.|.|||.|.|  ......:||..
Human   209 DQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKI--PEFNSIIGQRL 271

  Fly   236 GPSEGDWTKIRLMYKC 251
            ..|..|..::..||.|
Human   272 DFSAIDLERLNRMYNC 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	63/191 (33%)
MEP1A	XP_011512930.1	ZnMc_meprin	58..287	CDD:239809	73/209 (35%)
		MAM	292..459	CDD:214533
		MATH_Meprin_Alpha	459..622	CDD:239752
		EGF	702..736	CDD:394967