DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and mep1bb

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_009294699.1	Gene:	mep1bb / 327586	ZFINID:	ZDB-GENE-030131-5797	Length:	774	Species:	Danio rerio

Alignment Length:	235	Identity:	78/235 - (33%)
Similarity:	109/235 - (46%)	Gaps:	31/235 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GIESYENYYNEIHIDDEQAEAKTRNALTSPLQRWPGNKILYRISTDYSEQEVANVRTAMSSFGEQ 88
            |::.:|   .:|..|    |...||::.....||| ..|.|....|........:..|...:..:
Zfish    57 GLDLFE---GDILYD----ETLGRNSIIGEEYRWP-KTIPYYFEDDLEINAKGVILKAFEQYRLK 113

  Fly    89 TCVQFEEIEGAPPAGKRYVSFKKSPNMC-----GTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHE 148
            ||:.::...|.    :.|:|..|. |.|     ..|||.|.||.|       ..|..: |.|:||
Zfish   114 TCIDYKPWTGE----ENYISVFKG-NGCFSSVGNRRVGRQTLSIG-------SGCDRI-ATIEHE 165

  Fly   149 TLHLLGLFHEQSRPDRDEYVQIDYDNIPRKYWSQFMAMDQTTT--FNVPYDYESVMHYSKNAFAK 211
            .||.||.:|||||.|||:||.|.:|.|.......|...:.:::  .||||||.|:||||:.|| :
Zfish   166 FLHALGFWHEQSRSDRDDYVSIMWDRITEGKEHNFNKYNDSSSSALNVPYDYSSMMHYSQKAF-Q 229

  Fly   212 DPSKPTIRALIGGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
            ..|:|||...|  .|....:||....|:.|..|:..:|.|
Zfish   230 SGSEPTIITRI--PAFSSVIGQRMEFSDSDLLKLNRLYNC 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	70/202 (35%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	66/196 (34%)
mep1bb	XP_009294699.1	ZnMc	39..267	CDD:294052	77/233 (33%)
		Astacin	81..269	CDD:279708	71/204 (35%)
		MAM	277..441	CDD:279023
		MAM	277..440	CDD:99706
		MATH	440..608	CDD:295307
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910