DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and Mep1a

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_037275.1	Gene:	Mep1a / 25684	RGDID:	3080	Length:	748	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	74/209 - (35%)
Similarity:	101/209 - (48%)	Gaps:	14/209 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KTRNALTSPLQRWPGNKILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGKRYVSF 109
            :|||||..|..||. ..|.|.::.:........:..|...|..::||.|:..||.    ..|:.|
  Rat    64 RTRNALRDPSSRWK-PPIPYILADNLDLNAKGAILNAFEMFRLKSCVDFKPYEGE----SSYIIF 123

  Fly   110 KKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDN 174
            ::... |.:.||.|.:.   ..:.:.|.| ...|:|:||.||.||.||||||.|||:||.|.::.
  Rat   124 QQFSG-CWSMVGDQHVG---QNISIGEGC-DYKAIIEHEILHALGFFHEQSRTDRDDYVNIWWNE 183

  Fly   175 IPRKYWSQFMAMDQ--TTTFNVPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGP 237
            |...|...|...|.  .|..|.||||||:|||...:|.|:.:.|||...|  ......:||....
  Rat   184 IMTDYEHNFNTYDDKTITDLNTPYDYESLMHYGPFSFNKNETIPTITTKI--PEFNAIIGQRLDF 246

  Fly   238 SEGDWTKIRLMYKC 251
            |..|.|::..||.|
  Rat   247 SATDLTRLNRMYNC 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	67/197 (34%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	63/191 (33%)
Mep1a	NP_037275.1	ZnMc	32..260	CDD:294052	73/207 (35%)
		Astacin	75..261	CDD:279708	68/198 (34%)
		MAM	270..433	CDD:279023
		MAM	270..432	CDD:99706
		MATH	432..596	CDD:295307
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	641..668
		EGF	676..710	CDD:278437
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910