DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and nas-32

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_503351.3	Gene:	nas-32 / 178595	WormBaseID:	WBGene00003550	Length:	653	Species:	Caenorhabditis elegans

Alignment Length:	208	Identity:	65/208 - (31%)
Similarity:	89/208 - (42%)	Gaps:	24/208 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 NEI-HIDDEQAEAKTR--NALTSPLQRWPGNKILYRISTDYSEQEVANVRTAMSSFGEQTCVQFE 94
            |:| .|..||:....|  ..:.:..|.|||..:.|...:..:......||.|::.....||::||
Worm   185 NQIAKISSEQSSKSRRKKRQIDNLAQFWPGKVVYYYFDSGLTTTVQQIVRDAITFLESNTCLKFE 249

  Fly    95 EIEGAPPAGKRY--VSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFH 157
            ....|....|.:  |.......|.|   |.|.||.|       ..| .:.....||..|.|||||
Worm   250 LNSTATNRVKIFSGVGCYSDTGMLG---GEQTLSLG-------YGC-EVTGTAAHEIAHTLGLFH 303

  Fly   158 EQSRPDRDEYVQIDYDNIPRKYWSQFMAMDQTTTFN-VPYDYESVMHYSKNAFAKD-------PS 214
            .|.|.|||:||.||..::|......|:.:.:.|:.| |.|:|.|.||||..||...       |.
Worm   304 TQMRSDRDDYVTIDLTDVPESSQQNFIKLTEATSTNLVDYEYGSFMHYSGRAFVSSGGVDSIVPK 368

  Fly   215 KPTIRALIGGKAV 227
            .|.:...:||:.|
Worm   369 DPVMVYTMGGRIV 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	59/183 (32%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	56/179 (31%)
nas-32	NP_503351.3	Astacin	210..397	CDD:279708	59/183 (32%)
		ZnMc_astacin_like	214..393	CDD:239807	56/179 (31%)
		CUB	464..>528	CDD:294042
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14369
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.920