DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and nas-36

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	NP_492109.2	Gene:	nas-36 / 172506	WormBaseID:	WBGene00003552	Length:	617	Species:	Caenorhabditis elegans

Alignment Length:	186	Identity:	59/186 - (31%)
Similarity:	87/186 - (46%)	Gaps:	14/186 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 IDDEQAEAKTRNALTSPLQRWPGNKILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPP 101
            :..::.:...|:.::.....|....|.||.........::.:..|:..:.:.||:.||.:..:|.
Worm   116 LSKDKTKRLRRSFVSDKTATWKTMPIKYRFHESIDFYTISQIIAAIRFWEDSTCITFENVSDSPD 180

  Fly   102 AGKRYVSFKKSP---NMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPD 163
            ..  |:.|....   :|.|...|.|.:|.|       |.|:.| .||:||..|.|||:|||||||
Worm   181 GD--YIEFFSGQGCYSMIGRNGGRQGISIG-------ESCVKM-GVIEHEIGHALGLWHEQSRPD 235

  Fly   164 RDEYVQIDYDNIPRKYWSQFMAM-DQTTTFNVPYDYESVMHYSKNAFAKDPSKPTI 218
            ...||.|:.|.|...|.|.|:.. |:..|..:|||..|||||...||:.|....|:
Worm   236 ALGYVTIERDFILPSYISDFLQRDDEIDTLGIPYDLGSVMHYGSTAFSVDQKSKTV 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	58/168 (35%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	57/164 (35%)
nas-36	NP_492109.2	Astacin	134..323	CDD:279708	58/168 (35%)
		ZnMc_astacin_like	140..320	CDD:239807	57/162 (35%)
		CUB	380..478	CDD:214483
		TSP1	510..556	CDD:214559
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3714
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14369
orthoMCL	1	0.900	-	-		OOG6_111101
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6486
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.720