DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and LOC105946018

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031756313.1	Gene:	LOC105946018 / 105946018	-ID:	-	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	77/249 - (30%)
Similarity:	110/249 - (44%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IFAPNLVASEGIESYENYYNEI-HIDDEQAEAKTRNALTSPLQRWPGNK----ILYRISTDYSEQ 73
            :|:..|.|::|        |.: .:.::.|...:|:|:||....|....    :.|.:.:.||..
Frog   124 VFSRILKANQG--------NGVPRVQEDIAVGVSRSAITSTECLWQKTNETVYVPYTLDSKYSNS 180

  Fly    74 EVANVRTAMSSFGEQTCVQF----EEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVL 134
            ||..:.:||..:...|||||    :|.:        ||:. .|.:.|.:.:|.|    |..:||.
Frog   181 EVNTMTSAMEVYATLTCVQFVPYTDEDD--------YVNI-TSGDGCWSYMGRQ----GGAQVVS 232

  Fly   135 NEK--CLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDNIPRKYWSQFMAMDQTTTFNVPYD 197
            .||  | |......||..|.||..||.||.|||.||.|.|..|.......|..|: |...|..||
Frog   233 VEKGYC-TSEGTTMHELNHALGFVHEHSRSDRDNYVNIMYQYISPGDIVNFEIMN-TNNLNTIYD 295

  Fly   198 YESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
            |.|:|||...||:....|.||.|.:....:   :|.....:..|..||..:|:|
Frog   296 YRSIMHYPAWAFSNTTGKNTIVAKLNPNII---IGAGSTMTSLDIIKINRLYEC 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	66/205 (32%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	64/199 (32%)
LOC105946018	XP_031756313.1	C2	92..>113	CDD:417471
		ZnMc	164..346	CDD:412141	65/199 (33%)
		CUB	349..458	CDD:395345
		CUB	463..574	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020