DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and astl

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031755136.1	Gene:	astl / 101730245	XenbaseID:	XB-GENE-5769376	Length:	972	Species:	Xenopus tropicalis

Alignment Length:	224	Identity:	58/224 - (25%)
Similarity:	98/224 - (43%)	Gaps:	35/224 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 EAKTRNALTSPLQRWP---GNKIL-YRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAG 103
            |.::....::...:||   |:.|: |.:|:.|...:...:..|.......||::|.|    ....
Frog    62 EKRSIRTFSARFAKWPKINGSVIIPYTLSSSYESFDRNIILKAFRDLQASTCLRFVE----RTTE 122

  Fly   104 KRYVSFKKSPNMCGT--RVGYQPLSFGPHEVVLNEKCLTM---PAVIQHETLHLLGLFHEQSRPD 163
            :.|::.:.:.....:  |||      |...|.|..:||..   ..:..||.:|:.|.:||.||.|
Frog   123 RDYIAIEPAIGCFSSVGRVG------GMQLVSLAFECLRTDKGKGIALHELMHVAGFWHEHSRAD 181

  Fly   164 RDEYVQIDYDNIPRKYWSQFMAMDQTTTFNVPYDYESVMHYSKNAFAK------DPSKPTIRALI 222
            ||:|:.|.:|.|...|...|... .||...|.|:.:|::||.::||:|      :|..|..:.
Frog   182 RDDYIWIIWDEILIGYEKNFCKY-ATTNMLVKYELQSILHYPRSAFSKSGQATINPKYPYSKI-- 243

  Fly   223 GGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
                   |:||....|..|..::..:|.|
Frog   244 -------EIGQREKLSASDILRVNKLYSC 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	56/210 (27%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	53/201 (26%)
astl	XP_031755136.1	ZnMc_astacin_like	84..263	CDD:239807	52/198 (26%)
astl	XP_031755136.1	MAM	817..971	CDD:99706
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.110