DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and astl2g

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_002934115.1	Gene:	astl2g / 100491886	XenbaseID:	XB-GENE-22069768	Length:	505	Species:	Xenopus tropicalis

Alignment Length:	286	Identity:	82/286 - (28%)
Similarity:	118/286 - (41%)	Gaps:	66/286 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLAGIFAPNLVASEGIESYENYYNEIHIDDEQAEAKTRNALT---------------------- 51
            |::|.:.  ..:....:|.|....|:|.:..|:|:.:.::..|
Frog     8 LIVASLM--QCILGAPLEIYFEEANKIAVSQEEAKPEPKDVFTIISETNKGVKKLLHESDIVVSV 70

  Fly    52 --------SPLQRWPGN----KILYRISTDYSEQEVANVRTAMSSFGEQTCVQF-------EEIE 97
                    ....||..:    ::.|.||.::|..||:.:..||..|...|||.|       :.::
Frog    71 DRNAMKCDGDTCRWKTSDGIVRVPYTISANFSATEVSVIVDAMQDFATLTCVNFVPRTVEPDYLQ 135

  Fly    98 GAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRP 162
            ..|.:|            |.:.||   .:.|..||.||:........:|||..|.||.:|||||.
Frog   136 IIPDSG------------CWSYVG---KTGGAQEVSLNQGGCVGKGTVQHELNHALGFYHEQSRS 185

  Fly   163 DRDEYVQIDYDNIPRKYWSQFMAMDQTTTFNV--PYDYESVMHYSKNAFAKDPSKPTIRALIGGK 225
            |||.||.|...||.......|   |:..|.|:  .|||.|||||.:|||||.|...||   :...
Frog   186 DRDNYVNILTGNIIPASIGNF---DKYNTNNLGQEYDYSSVMHYGRNAFAKQPGLDTI---VPKP 244

  Fly   226 AVEREMGQVRGPSEGDWTKIRLMYKC 251
            .....:||..|.|..|.:||..:|:|
Frog   245 NPNVPIGQRYGLSNLDISKINQLYQC 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	72/208 (35%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	69/202 (34%)
astl2g	XP_002934115.1	Astacin	83..272	CDD:279708	73/209 (35%)
		ZnMc_hatching_enzyme	88..270	CDD:239810	70/202 (35%)
		CUB	270..384	CDD:238001	1/1 (100%)
		CUB	387..497	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020