DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and astl3c

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_002937470.2	Gene:	astl3c / 100491451	XenbaseID:	XB-GENE-22069695	Length:	533	Species:	Xenopus tropicalis

Alignment Length:	272	Identity:	87/272 - (31%)
Similarity:	118/272 - (43%)	Gaps:	49/272 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LLAGIFAPNLVASEGIESYE-NYYNEIHID--DEQAEAKTRN---------------ALTSPLQR 56
            |..||.|...:..|..:|.. |...|..:|  .:.|||...|               :.||....
Frog    29 LADGITASKEILEENKKSGPGNKKPESSVDVFTQIAEANKGNMALTEGGDILINIGRSATSSDYL 93

  Fly    57 WP----GNKIL-YRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGKR----YVSFKKS 112
            ||    |..:: |..|.:||..|:...:|||..|...|||:|     .|...:|    .||....
Frog    94 WPKSADGTVVVPYIFSYNYSADELTLFKTAMQEFETLTCVRF-----VPKTIQRDFLNIVSNGGC 153

  Fly   113 PNMCGTRVGYQPL---SFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDN 174
            .:|.|...|.|.:   |:|         |::. .|||||..|.||.:||..|.|||:||.|..:|
Frog   154 LSMVGRNGGGQKVELASYG---------CMSR-GVIQHELNHALGFYHEHMRSDRDDYVTIITEN 208

  Fly   175 IPRKYWSQFMAMDQTTTFNVPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGPSE 239
            |...| ..:.:..:|....:.|||.||||||:|.|:..|.|.||   :........:||..|.|.
Frog   209 IIPSY-ENYFSKRKTNNMGIIYDYNSVMHYSRNTFSISPDKSTI---VPKPDPSIPIGQRDGLSI 269

  Fly   240 GDWTKIRLMYKC 251
            .|..||:.:|:|
Frog   270 LDILKIKKLYQC 281

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	71/207 (34%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	68/197 (35%)
astl3c	XP_002937470.2	ZnMc	99..281	CDD:381785	69/200 (35%)
		CUB	290..393	CDD:366096
		CUB	398..508	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10127
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020