DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and astl3b.2

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031746779.1	Gene:	astl3b.2 / 100491112	XenbaseID:	XB-GENE-22069683	Length:	529	Species:	Xenopus tropicalis

Alignment Length:	225	Identity:	73/225 - (32%)
Similarity:	101/225 - (44%)	Gaps:	44/225 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KTRNALTSPLQRWP----GNKIL-YRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGK 104
            |.|:|:......||    |..|: |..|::||..::|..::.|..:...|||:|     .|.|.:
Frog   104 KGRSAMNCTECLWPKSTDGTVIVPYNFSSNYSADQLALFKSTMQEYESLTCVRF-----VPRANE 163

  Fly   105 RYVSFKKSPNMCGT---RVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDE 166
            .......|.|.|.:   :||      |...|.|:........:||||..|.||.:|||||.|||:
Frog   164 TDFLSIVSDNGCASFLGKVG------GDQTVQLDSYGCIYRGIIQHELNHALGFYHEQSRSDRDD 222

  Fly   167 YVQIDYDNIPRKYWSQFMAMDQTTTFNVPYDYESVMHYSKNAFAK----------DPSKPTIRAL 221
            ||.|..:||...|...|...| :....:.|||.|||||..:||:|          ||:.|
Frog   223 YVTIHTENIIPGYEGNFNKAD-SNNLGLEYDYSSVMHYPGDAFSKNGNLTIVPKPDPTVP----- 281

  Fly   222 IGGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
                     :||..|.|..|.:||..:|:|
Frog   282 ---------IGQRDGLSILDVSKINRLYQC 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	69/213 (32%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	66/203 (33%)
astl3b.2	XP_031746779.1	ZnMc_hatching_enzyme	121..302	CDD:239810	67/206 (33%)
		CUB	306..414	CDD:238001
		CUB	419..527	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010