DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and XB5949052

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_002932488.2	Gene:	XB5949052 / 100489456	XenbaseID:	XB-GENE-5949053	Length:	453	Species:	Xenopus tropicalis

Alignment Length:	213	Identity:	64/213 - (30%)
Similarity:	99/213 - (46%)	Gaps:	18/213 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KTRNALTSPLQRWPGN-----KILYRISTDYSEQEVANVRTAMSSFGEQTCVQFEEIEGAPPAGK 104
            |:.|.....:..||.:     :|.|.||:|||....|..:.:...|.:.||::.     .|...:
Frog    75 KSANTCPKGICLWPKSSDGLVRIPYVISSDYSSYSNALFQASFKGFADTTCIRL-----VPRTSE 134

  Fly   105 R-YVSFKKSPNMCGTRVGYQPLSFGPHEVVLNEKCLTMPAVIQHETLHLLGLFHEQSRPDRDEYV 168
            . |:|| :|.|.|.:.:|   .:.|...|.:.:......::|:||.:|.|||.||..|.|||:||
Frog   135 TDYLSF-ESLNGCWSPIG---RTGGAQTVSVQQSGCMWTSIIEHEIIHSLGLHHEHVRSDRDKYV 195

  Fly   169 QIDYDNIPRKYWSQFMAMDQTTTFNVPYDYESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQ 233
            .:.::||.......|...|........|||.|:||||..||:.:.:.||:.|:.....   ..|.
Frog   196 SVQWNNISPGNTGNFQMTDTNNMNLTKYDYNSLMHYSSTAFSINGNLPTLIAVPDSSV---SFGN 257

  Fly   234 VRGPSEGDWTKIRLMYKC 251
            ....|:.|..|:..:|||
Frog   258 AFMMSDLDIKKLNTLYKC 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	60/201 (30%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	57/195 (29%)
XB5949052	XP_002932488.2	ZnMc	92..275	CDD:412141	58/194 (30%)
XB5949052	XP_002932488.2	CUB	342..452	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D472790at33208
OrthoFinder	1	1.000	-	-		FOG0000240
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920