DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6974 and LOC100488711

DIOPT Version :9

Sequence 1:	NP_650414.1	Gene:	CG6974 / 41815	FlyBaseID:	FBgn0038285	Length:	251	Species:	Drosophila melanogaster
Sequence 2:	XP_031756326.1	Gene:	LOC100488711 / 100488711	-ID:	-	Length:	497	Species:	Xenopus tropicalis

Alignment Length:	249	Identity:	77/249 - (30%)
Similarity:	110/249 - (44%)	Gaps:	37/249 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 IFAPNLVASEGIESYENYYNEI-HIDDEQAEAKTRNALTSPLQRWPGNK----ILYRISTDYSEQ 73
            :|:..|.|::|        |.: .:.::.|...:|:|:||....|....    :.|.:.:.||..
Frog    42 VFSRILKANQG--------NGVPRVQEDIAVGVSRSAITSTECLWQKTNETVYVPYTLDSKYSNS 98

  Fly    74 EVANVRTAMSSFGEQTCVQF----EEIEGAPPAGKRYVSFKKSPNMCGTRVGYQPLSFGPHEVVL 134
            ||..:.:||..:...|||||    :|.:        ||:. .|.:.|.:.:|.|    |..:||.
Frog    99 EVNTMTSAMEVYATLTCVQFVPYTDEDD--------YVNI-TSGDGCWSYMGRQ----GGAQVVS 150

  Fly   135 NEK--CLTMPAVIQHETLHLLGLFHEQSRPDRDEYVQIDYDNIPRKYWSQFMAMDQTTTFNVPYD 197
            .||  | |......||..|.||..||.||.|||.||.|.|..|.......|..|: |...|..||
Frog   151 VEKGYC-TSEGTTMHELNHALGFVHEHSRSDRDNYVNIMYQYISPGDIVNFEIMN-TNNLNTIYD 213

  Fly   198 YESVMHYSKNAFAKDPSKPTIRALIGGKAVEREMGQVRGPSEGDWTKIRLMYKC 251
            |.|:|||...||:....|.||.|.:....:   :|.....:..|..||..:|:|
Frog   214 YRSIMHYPAWAFSNTTGKNTIVAKLNPNII---IGAGSTMTSLDIIKINRLYEC 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6974	NP_650414.1	Astacin	55..251	CDD:279708	66/205 (32%)
CG6974	NP_650414.1	ZnMc_astacin_like	59..249	CDD:239807	64/199 (32%)
LOC100488711	XP_031756326.1	ZnMc	82..264	CDD:412141	65/199 (33%)
		CUB	276..373	CDD:214483
		CUB	378..489	CDD:238001
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D681837at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010