DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14861 and efhd2

DIOPT Version :9

Sequence 1:	NP_650409.1	Gene:	CG14861 / 41810	FlyBaseID:	FBgn0038280	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_001313422.1	Gene:	efhd2 / 571114	ZFINID:	ZDB-GENE-060531-152	Length:	233	Species:	Danio rerio

Alignment Length:	209	Identity:	69/209 - (33%)
Similarity:	97/209 - (46%)	Gaps:	41/209 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   176 TVTSEDSDCDYEL----SLDE---VHQR-----FSAW-----FNQKEIDTAYSCFTQMDEDLDGY 223
            |.:|.||:...:|    .|:|   .||:     |:.:     |::|:|......|.|.|.:.|.|
Zfish    40 TTSSADSELGAKLQRRGELNEGVGEHQQPSMKVFNPYTEFKEFSRKQIKDMEKMFKQYDSEKDNY 104

  Fly   224 ISLGELKRFLEKLEMPQTHLATKNVMTHVVGNHLERLTFCHALLIYGTVLNRLELRK---GHLLD 285
            |.|.|||..:|||..|||||..||::..|..:...:|:|...|||:         ||   |.|.:
Zfish   105 IDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDLDGKLSFREFLLIF---------RKAAAGELAE 160

  Fly   286 RERLR-LARSKAVDVSKVGVSGAKQFFEAKIAMQSDPLPPINSDQPVARIAVHSLN-----TENP 344
            ...|. |||...:|||..||.|||.|||||:...::      |::..|.|.:....     .|..
Zfish   161 DSGLHVLARLSEIDVSTEGVKGAKSFFEAKVQAINE------SNRFEAEIRLEQEEKKKQAEEKK 219

  Fly   345 GRRVNFKSAAALFK 358
            .|:..||...:.||
Zfish   220 QRQAAFKELKSAFK 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14861	NP_650409.1	None
efhd2	NP_001313422.1	EFh	89..147	CDD:238008	23/57 (40%)
efhd2	NP_001313422.1	EF-hand_7	90..147	CDD:290234	23/56 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580521
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0041
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1511376at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13025
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.810