DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14861 and Efhd2

DIOPT Version :9

Sequence 1:	NP_650409.1	Gene:	CG14861 / 41810	FlyBaseID:	FBgn0038280	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_080270.2	Gene:	Efhd2 / 27984	MGIID:	106504	Length:	240	Species:	Mus musculus

Alignment Length:	169	Identity:	59/169 - (34%)
Similarity:	80/169 - (47%)	Gaps:	27/169 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 FNQKEIDTAYSCFTQMDEDLDGYISLGELKRFLEKLEMPQTHLATKNVMTHVVGNHLERLTFCHA 265
            |::|:|......|.|.|...||:|.|.|||..:|||..|||||..|:::..|..:...:|:|...
Mouse    89 FSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIQEVDEDFDSKLSFREF 153

  Fly   266 LLIYGTVLNRLELRK---GHLLDRERLR-LARSKAVDVSKVGVSGAKQFFEAKIAMQSDPLPPIN 326
            |||:         ||   |.|.:...|. |||...:|||..||.|||.|||||:       ..||
Mouse   154 LLIF---------RKAAAGELQEDSGLHVLARLSEIDVSTEGVKGAKNFFEAKV-------QAIN 202

  Fly   327 SDQPVARIAVHSLNTENPGRR---VNFKSAAALFKKLEN 362
                |:......:..|...|:   ...|...|.||:|::
Mouse   203 ----VSSRFEEEIKAEQEERKKQAEEVKQRKAAFKELQS 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14861	NP_650409.1	None
Efhd2	NP_080270.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..51
		EFh	96..154	CDD:238008	22/57 (39%)
		EF-hand_7	97..154	CDD:290234	22/56 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836984
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0041
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1511376at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13025
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	7	6.760