Protein Alignment Sdr and Insrr

DIOPT Version :10

• Sequence 1: NP_650408.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: XP_063138512.1
• Gene: Insrr / 60663
• RGDID: 67399
• Length: 1359
• Species: Rattus norvegicus
• Alignment Length: 974
• Identity: 264/974 - (27%)
• Similarity: 411/974 - (42%)
• Gaps: 244/974 - (25%)

  Fly    14 PISIAVPLILLFLGASSPVLASSDDQTACGSLEI-NKIADLRKLQNCTHVVGHVRLAYV------ 71
            |..:.:.:.||.||      :..|....|.||:| :::.:||:|:||:.|.||:::..:
  Rat     8 PWGVYLLMSLLSLG------SCLDTLEVCPSLDIRSEVTELRRLENCSVVEGHLQILLMFAATGE 66

  Fly    72 DLTDVSGNYSLDSLASNVTEISDYLMVYRCTGLISLQSIFPRLRIIRGQELLFDQYSLVVYENRN 136
            |...:|        ...:|:::|||:::|..||.||:.:||.|.:|||.. ||..|:|:::|..:
  Rat    67 DFRGLS--------FPRLTQVTDYLLLFRVYGLESLRDLFPNLAVIRGAR-LFLGYALIIFEMPH 122

  Fly   137 LRELGLVELLRIQSGFIRVESNPLLCFVETVDWIYLMGNATRQHFSLKHNRPQSQC-PLC-GSLS 199
            ||::||..|..:..|.:|||.|..||.:.|:||..|.......|  :..|:...:| .:| |.|.
  Rat   123 LRDIGLPSLGAVLRGAVRVEKNQELCHLSTIDWGLLQPAPGANH--IVGNKLGEECADVCPGVLG 185

  Fly   200 ADFE------FIRNSSERCWNVNTTQLRPQPPRLKDCPIACGLNGCDSAGKCCDHNCVTGCYS-- 256
            |..|      |..::..|||..:..|        :.||...|| .|...|:||...|:.||..
  Rat   186 AAGEPCVRTTFGGHTDYRCWTSSHCQ--------RVCPCPRGL-ACTVGGECCHSECLGGCSQPE 241

  Fly   257 --QNCSLCANYQGRMGCVNQC-VASYELNKRRCIGHRECRELGRIP-------LIRGYQCVKKCP 311
              :.|..|.:...:..|:..| ..:|:....||:....|..|..:|       :..| .|:.:||
  Rat   242 DPRACVACRHLYFQGVCLPTCPPGTYQYESWRCVTAELCGHLREVPGHATAFGIYEG-SCLAQCP 305

  Fly   312 ----GNQKEILVAKGIIHCQVECN----------------GDFHVKSAADLEVLQDCVTINGS-- 354
                .|...|...|....|..||.                |..||:.:..|.:.|.|...:.|
  Rat   306 PGFTRNGSSIFCHKCEGLCPKECKVGTKTIDSVQATQDLVGCTHVEGSLILNLRQGCQYSSWSRP 370

  Fly   355 -------------------------LTIELTNI----------------KEKIVDALENALASVK 378
                                     |:::|.::                .:.:...|:..|..|:
  Rat   371 WPRPPWSHPPSLAWFPLIPPFLPPRLSLQLPSLWTHHLPWPAPLLSFSSPDNLEPELQRNLGLVE 435

  Fly   379 EITGYLKVIHSAQLMSLTFLQNLDAIRGDKLVENKYALYVVNNYHLEHI--WPPNHLVIIQRGTL 441
            .|||:||:.||..|::|.|.:||..||||.:|:..|.|||::|.:|:.:  |....|. |..|.:
  Rat   436 TITGFLKIKHSFALVTLGFFKNLKLIRGDSMVDGNYTLYVLDNQNLQQLGSWVAAGLT-IPVGKI 499

  Fly   442 FFHLNPRLCYEKIHQLQGSLKSGENISVADVSPNSNGERVICGDAVRSL----NPKVEDLNSTAV 502
            :|..|||||.|.|:||:....:....|.|:::|.:||:|..|  ..|:|    |...||
  Rat   500 YFAFNPRLCLEHIYQLEEVTGTRGRQSKAEINPRTNGDRAAC--QTRTLRFVFNLTEED------ 556

  Fly   503 RIILDYMDWEGMET--LIGYSYHYKEAPVQNVTMYDGRHGCGHDNW-LMDVVPNQSRRH----VI 560
            ||:|.:..:|.:|.  |:.:..:|||:|.||.|.:.|...||..:| |:||....||..    .:
  Rat   557 RILLRWERYEPLEARDLLSFIVYYKESPFQNATEHVGPDACGTQSWNLLDVELPLSRTQEPGVTL 621

  Fly   561 SGLKPYTQYAYFVK--TLTRTEYHIQIDAYSKIGYFQTLPDRPSPVLRIYGSSEISSQILLHWWP 623
            :.|||:||||.||:  |||..|......|.|.|.|.:|||..|:....:..:|..||.:|:.|.|
  Rat   622 APLKPWTQYAVFVRAITLTTAEDSPHQGAQSPIVYLRTLPAAPTVPQDVISTSNSSSHLLVRWKP 686

  Fly   624 PRRPNGVIKNYFVTAEKYNATKEAKDKN-YVN------------------------VELENAKDI 663
            |.:.||.|..|.|..::.     |:|.: |:|                        :|.|..:..
  Rat   687 PVQRNGNITYYLVLWQRL-----AEDGDLYINDYCHRGLRLPTSSHDTRFDREDPALEAEPEQGC 746

  Fly   664 DCECAGVLPYYSGPQPDDEDYYNKEQITYEDALPNLIYVSRNHDYRRKEFEKVINYEHLLSIKKD 728
             |.|....|..:.|.      ...:::|::                 |:||..::  |.::|.|
  Rat   747 -CPCQHSPPGQALPA------LEAQEVTFQ-----------------KKFENFLH--HAITIPK- 784

  Fly   729 EEPTRPPTTTPAPTNATLAKERLAAINYENYRLNSEKKQRDLQDLDQHKYTIRHALPKCQNSHAS 793
                       ||...|       :|| :|.:.:||:.:|:...|...|          .||...
  Rat   785 -----------APWKVT-------SIN-KNPQRDSERHRRETGLLRLGK----------NNSDFE 820

  Fly   794 VVQQVEEKCVAEEPLSGYELPGTQHFYCLSQLEPETHYRITIRACVEGV-VNGCSTPAEAVIKT 856
            :   .|:|...|..:    |.|.:||         |.|||.|.||.... ..|||.......:|
  Rat   821 I---HEDKVPRERAV----LSGLRHF---------TEYRIDIHACNHAAHTVGCSAATFVFART 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_650408.1	Recep_L_domain	58..173	CDD:460032	42/120 (35%)
		Furin-like	210..332	CDD:395614	35/153 (23%)
		Recep_L_domain	347..461	CDD:460032	44/158 (28%)
		FN3	491..578	CDD:214495	36/95 (38%)
Insrr	XP_063138512.1	None