DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sdr and Tie

DIOPT Version :9

Sequence 1:	NP_001287331.1	Gene:	Sdr / 41809	FlyBaseID:	FBgn0038279	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_523928.1	Gene:	Tie / 38559	FlyBaseID:	FBgn0014073	Length:	1233	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	56/315 - (17%)
Similarity:	97/315 - (30%)	Gaps:	115/315 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   520 YSYHYKE---------------APVQNVTMY--DGRHGCGHDNWLMDVVPNQSR------RHVIS 561
            |.||.:|               ||..:.|.|  .||...|..:.:.|:...:|.      |.|:.
  Fly   418 YKYHMRERGLVPTAAPPPAAPPAPPVSRTRYVGSGRPTAGLSDSIQDLKQTESEVAKPVVRRVVQ 482

  Fly   562 GLKPYTQYAYFVKTLTRTEYHIQIDAYSKIGYFQTLP--------------DRPS---------- 602
            .:.|.:.....:..|:..|       .:.:|..:.||              ::||
  Fly   483 KVSPSSSTPLIITVLSAEE-------ETTVGQTEALPTDESTTTTSTTTTTEKPSTTTSTSTTTT 540

  Fly   603 -PVLRIYGSSEISSQILLHWWPPRRPNGVIKNYFVTAE----------KYNATKEAKDKNYV--- 653
             ||......:..::.:.....|....:....:...|:.          |.|:..| |||..:
  Fly   541 TPVPSTSKRTTTNAPLSTTNTPTTTTSSTTPSTTTTSSTSTTVIPTTTKANSIIE-KDKELIRAL 604

  Fly   654 ------NVELENAKDI--------DCECAGVLPYYSGPQPDDEDYYNKEQITYEDALPNLIYVSR 704
                  .:.:::|.::        ||   ||.| .:..||...          .|:.|
  Fly   605 GPALTREINIDDANNLIVFCNNTSDC---GVTP-RTQTQPSHT----------TDSSP------- 648

  Fly   705 NHDYRRKEFEKVINYEHLLSIKKDEEPTRPPTTTPAPTNATLAKERLAAINYENY 759
                      |::....|.||:....| ||.:|:...:..|.|...:.|.:.|.|
  Fly   649 ----------KILRTTVLTSIRSTVHP-RPTSTSTTTSTTTTAPPAVTAPSNEVY 692

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_001287331.1	Recep_L_domain	58..173	CDD:279382
		Furin-like	209..332	CDD:279142
		Recep_L_domain	347..461	CDD:279382
		FN3	491..578	CDD:214495	17/80 (21%)
Tie	NP_523928.1	TyrKc	854..1183	CDD:197581
Tie	NP_523928.1	PTKc	860..1187	CDD:270623
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455321
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930