Protein Alignment Sdr and Nrk

DIOPT Version :10

• Sequence 1: NP_650408.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_477255.1
• Gene: Nrk / 36445
• FlyBaseID: FBgn0020391
• Length: 724
• Species: Drosophila melanogaster
• Alignment Length: 814
• Identity: 145/814 - (17%)
• Similarity: 247/814 - (30%)
• Gaps: 251/814 - (30%)

  Fly   115 RIIRGQELLFDQYSLVVYENRNLRELGLVELLRIQSGFIRVESNPLLCFVETVDWIYLMGNATRQ 179
            |::||         :|:....||..|||...|...:    ..:|.|....|.|         ||:
  Fly    12 RVLRG---------MVLKWGANLAVLGLCVFLFASA----THANSLNAIEEPV---------TRR 54

  Fly   180 HFSLKHNRPQSQCPLCGSLSADFEFIRNSSERCWNVNTTQLRPQPPRLKDCPIACGLNGCDSAGK 244
            |....|.|.:.:...|...         |.:.|....|.|            :...|.  |..|.
  Fly    55 HHQRHHEREREENGYCAPY---------SGKVCKEYLTGQ------------VWYSLE--DPTGG 96

  Fly   245 CCDHNCVTGCYSQNCS----LCANYQGRMGCVNQCVASYELNKRRCIGHRECRELGRIPLIRGYQ 305
            ..:....|..:.:..|    ||.....:|.|      :|..  ..|  |.|.....:.||
  Fly    97 WKNEQVTTALWDELISDLTGLCREAAEKMLC------AYAF--PNC--HMEGGRAVKAPL----- 146

  Fly   306 CVKKCPG-------NQKEILVAKGIIHCQVECNGDFHVKSAADL--------------------- 342
            |.:.|..       |...::..|...:..::..|.|.:.:.:.|
  Fly   147 CFEDCQATHLQFCYNDWVLIEEKKERNMFIKSRGHFRLPNCSSLPHYNASMRRPNCSYIGLTELK 211

  Fly   343 --EVLQDCVTINGSLTIELTNIKEKIVDALENALASVKEITGYLKVIHSAQLMSLTFLQNLDAIR 405
              ||..||...||...:...|:.       ::.:...:..|.|   .|......|.|.|.|:
  Fly   212 ESEVSYDCRNGNGRFYMGTMNVS-------KSGIPCQRWDTQY---PHKHFQPPLVFHQLLE--- 263

  Fly   406 GDKLVENK---------YAL----------------YVVNN-------YHLEHIWPPNHLVIIQR 438
            |:....|.         |.:                ||..|       ..:|..:.|: ::.:..
  Fly   264 GENYCRNAGGEEPHPWCYTVDESVRWQHCDIPMCPDYVDPNAVDLNTPIKMEKFFTPS-MIFLLA 327

  Fly   439 GTLF-----FHLNPRLCYEKIHQLQGSLKSGENISVADVSPNSNGERVICGDAVRSLNPKVEDL- 497
            |..|     .||...|.|:.......|..:|...:...||....|:   ||.   :||...|.|
  Fly   328 GIGFVAIVTLHLMILLVYKLSKHKDYSQPAGAATAECSVSMRGGGD---CGG---NLNTSRETLG 386

  Fly   498 ----------------------NSTAVRIILDYMDWEG------METLIGYSYHYKEAPVQNV-T 533
                                  |..|:..:.:..|.:|      :|.|     .|....:..| :
  Fly   387 GNGNTNTLAKWGTIRSTATIHSNCVALTTVTNVSDAKGTKPNARLEKL-----EYPRGDIVYVRS 446

  Fly   534 MYDGRHGCGHDNWLMDVVPNQSRRHVISGLKPYTQYAYFVKTL-TRTEYHIQIDAYSKIGYFQTL 597
            :..|..|.........:||:|....|.            ||.| ......:|:| :.:.......
  Fly   447 LGQGAFGRVFQARAPGLVPDQEDLLVA------------VKMLKDDASDQMQMD-FEREACLLAE 498

  Fly   598 PDRPSPVLRIYGSSEISSQ--ILLHWWPPRRPNGVIKNYFVTAEKYNATKEAKDKNYVNVE---- 656
            .|.|: ::|:.|...:...  :|..:..|    |.:..:......| ||.:|..::.:.:.
  Fly   499 FDHPN-IVRLLGVCALGRPMCLLFEYMAP----GDLSEFLRACSPY-ATHQAPTQDRLQLNELHL 557

  Fly   657 LENAKDIDCECAGVLPYYSGPQPDDEDYYNKEQITYEDALPNLIYVSRNHDYRRKEF---EKVIN 718
            |:.|.:|   .||:|            |.::.:..:.|.......::.:...:..:|   .|:..
  Fly   558 LQMAANI---AAGML------------YLSERKFVHRDLATRNCLINEHMAVKIADFGLSHKIYL 607

  Fly   719 YEHLLSIKKDEEPTRPPTTTPAPTNATLAKERLAAINYENYRLNSEKKQRDLQDLDQHKYTIRHA 783
            .::   .|.||....|....|           |.:|.|..:.|.|:.....:...:...:.::
  Fly   608 QDY---YKGDENDFIPIRWMP-----------LESILYNKFSLESDVWAYGICLWEVFSFALQ-- 656

  Fly   784 LPKCQNSHASVVQQVEE----KCVAEEPLSGYEL 813
             |....:|..|::.::|    .|....|||.|.|
  Fly   657 -PYFGLTHEEVIKYIKEGNVLGCPDNTPLSVYAL 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_650408.1	Recep_L_domain	58..173	CDD:460032	14/57 (25%)
		Furin-like	210..332	CDD:395614	22/132 (17%)
		Recep_L_domain	347..461	CDD:460032	26/150 (17%)
		FN3	491..578	CDD:214495	20/117 (17%)
Nrk	NP_477255.1	CRD_FZ	67..212	CDD:470581	27/182 (15%)
		KR	217..299	CDD:214527	15/94 (16%)
		PTKc_Musk	435..713	CDD:133181	54/306 (18%)