Protein Alignment Sdr and Ror

DIOPT Version :10

• Sequence 1: NP_650408.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_476962.1
• Gene: Ror / 34367
• FlyBaseID: FBgn0010407
• Length: 685
• Species: Drosophila melanogaster
• Alignment Length: 620
• Identity: 109/620 - (17%)
• Similarity: 200/620 - (32%)
• Gaps: 208/620 - (33%)

  Fly    78 GNYSLDSLASNVTEISDYLMVYR---CTGLISLQSIF--PRLRIIRGQELLFDQYSLVVYENRNL 137
            |::::||......:.|....:|.   |..::|...:|  |.|.:...:|.|...|. |:.|::::
  Fly    23 GSHNVDSRIYGFQQSSGICHIYNGTICRDVLSNAHVFVSPNLTMNDLEERLKAAYG-VIKESKDM 86

  Fly   138 RELGLVELLRIQSGFIRVESNPLLCF--------VETVDWIYLMGNATR----QHFSLKHNRPQS 190
                        :...|:.:.|.|||        .|..:.:|....||.    ::.|::..|.:|
  Fly    87 ------------NANCRMYALPSLCFSSMPICRTPERTNLLYFANVATNAKQLKNVSIRRKRTKS 139

  Fly   191 QCPLCGSLSADFEFI---RNSSERCWNVNTTQLRPQPPRLKD-------CPIAC----------- 234
            :         |.:.|   :..|....:|.:|.:..:.|..::       |...|
  Fly   140 K---------DIKNISIFKKKSTIYEDVFSTDISSKYPPTRESENLKRICREECELLENELCQKE 195

  Fly   235 ----------GLNGCDSAGKCCDH-NCVT-----------GCYSQNCSLCANYQGRMGCVNQCVA 277
                      |:.|.:...|...| :|::           .||.::.|   .|:|        ||
  Fly   196 YAIAKRHPVIGMVGVEDCQKLPQHKDCLSLGITIEVDKTENCYWEDGS---TYRG--------VA 249

  Fly   278 SYELNKRRC----------------IGHRECR---------------------ELGRIPLIRGYQ 305
            :...:.:.|                ||...||                     ||..||     :
  Fly   250 NVSASGKPCLRWSWLMKEISDFPELIGQNYCRNPGSVENSPWCFVDSSRERIIELCDIP-----K 309

  Fly   306 CVKK----CPGNQKEILV------------AKGIIHCQVE-------CNGDFHVKSAADLEVLQD 347
            |..|    ..|....|::            .:.|:|..:.       .:.|.::...:.|...||
  Fly   310 CADKIWIAIVGTTAAIILIFIIIFAIILFKRRTIMHYGMRNIHNINTPSADKNIYGNSQLNNAQD 374

  Fly   348 CVTIN-GSLTIELTNIKEKIVDALENALASVKEITGYLKVIHSAQLMSLTFLQNL------DAIR 405
            ....| |:|:..:. :..|:::  .|.|..:...|          |..:.||:.|      ...:
  Fly   375 AGRGNLGNLSDHVA-LNSKLIE--RNTLLRINHFT----------LQDVEFLEELGEGAFGKVYK 426

  Fly   406 GDKLVENKYALYVVNNYHLEHIWPPNHLVIIQRGTLFFHLNPRLCYEKIHQLQGSLKSGENISVA 470
            |..|..||..:.|......|     |..|..|:.           :::..:|...||....:.:.
  Fly   427 GQLLQPNKTTITVAIKALKE-----NASVKTQQD-----------FKREIELISDLKHQNIVCIL 475

  Fly   471 DVSPNSNG-----ERVICGDAVRSL--NPKVEDLNSTAVRII-LDYMDWEGMETLIGYSYHYKEA 527
            .|..|...     |.:..||....|  |...|..:.:.:..: :.....|||:.|..:.|.:::.
  Fly   476 GVVLNKEPYCMLFEYMANGDLHEFLISNSPTEGKSLSQLEFLQIALQISEGMQYLSAHHYVHRDL 540

  Fly   528 PVQNVTMYDG------RHGCGHDNWLMDVVPNQSR 556
            ..:|..:.:|      ..|...|.:..|....||:
  Fly   541 AARNCLVNEGLVVKISDFGLSRDIYSSDYYRVQSK 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_650408.1	Recep_L_domain	58..173	CDD:460032	22/107 (21%)
		Furin-like	210..332	CDD:395614	32/221 (14%)
		Recep_L_domain	347..461	CDD:460032	22/120 (18%)
		FN3	491..578	CDD:214495	14/73 (19%)
Ror	NP_476962.1	CRD_TK_ROR_like	39..228	CDD:143568	36/210 (17%)
		KR	235..312	CDD:214527	17/92 (18%)
		PTKc_Ror	404..673	CDD:270642	37/198 (19%)