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Protein Alignment Sdr and EPHA8

DIOPT Version :10

Sequence 1:	NP_650408.1	Gene:	Sdr / 41809	FlyBaseID:	FBgn0038279	Length:	868	Species:	Drosophila melanogaster
Sequence 2:	NP_065387.1	Gene:	EPHA8 / 2046	HGNCID:	3391	Length:	1005	Species:	Homo sapiens

Alignment Length:	392	Identity:	75/392 - (19%)
Similarity:	135/392 - (34%)	Gaps:	119/392 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 KDCP--------IACGLNGCDSA------GKCCDHNCVTGCYSQNCSLCANYQGRMG-CVNQCVA 277
            |.||        .:..:.|.||:      |:|..|:.........||....:...:| ||  |.|
Human   202 KKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCV--CSA 264

  Fly   278 SYELNKRRCIGHRECRELGRIPLIRGYQCVKKCPGNQKEILVAKGIIHCQVECNGDFHVKSAAD- 341
            .||..:..|:.   | |||......|.|...:||.:......|....||.:.     :.::|.|
Human   265 GYEERRDACVA---C-ELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLS-----YYRAALDP 320

  Fly   342 ------------LEVLQDCVTING-SLTIELTNIKEKIVDALENALASVKEITGYLKVIHSAQLM 393
                        :.::.   ::|| |:|:|               .|...:..|...:.::|...
Human   321 PSSACTRPPSAPVNLIS---SVNGTSVTLE---------------WAPPLDPGGRSDITYNAVCR 367

  Fly   394 SLTF-LQNLDAI-RGDKLVENKYALYVVNNYHLEHIWPPNHLVIIQRGTLFFHLNPRLCYEKIHQ 456
            ...: |...:|. .|.:.|..:.:|...:            |::   ..|..|:|.....|.::
Human   368 RCPWALSRCEACGSGTRFVPQQTSLVQAS------------LLV---ANLLAHMNYSFWIEAVN- 416

  Fly   457 LQGSLKSGENISVADVSPNSNGERVICGDAVRSLNPKV-----EDLNSTAVRIILDYMDWEGME- 515
                       .|:|:||......|:.....::...:|     |....|:|.::     |:..|
Human   417 -----------GVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLL-----WQEPEQ 465

  Fly   516 ---TLIGY--SYHYKEAPVQNVTMYDGRHGCGHDNWLMDVVPNQSRRHVISGLKPYTQYAYFVKT 575
               .::.|  .|:.|:..:|:.:                .:...:.|..:|||||.|:|.:.|:.
Human   466 PNGIILEYEIKYYEKDKEMQSYS----------------TLKAVTTRATVSGLKPGTRYVFQVRA 514

  Fly   576 LT 577
            .|
Human   515 RT 516

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.