Protein Alignment Sdr and rol-3

DIOPT Version :9

• Sequence 1: NP_001287331.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_001256097.1
• Gene: rol-3 / 179204
• WormBaseID: WBGene00004395
• Length: 2481
• Species: Caenorhabditis elegans
• Alignment Length: 970
• Identity: 174/970 - (17%)
• Similarity: 323/970 - (33%)
• Gaps: 362/970 - (37%)

  Fly    10 PLPIPISIAVPLI------LLFLGASSPVL--------ASSDDQ--------------TACGSLE 46
            |.|:|....:..|      .:.:|:|...|        .:.:||              |....:|
 Worm   354 PFPLPTDDTITAIAGISDTTIAIGSSKGSLWTYQMSANQTDEDQPSSVIQLKTVGEMDTKINQIE 418

  Fly    47 INKI---------------ADLRKLQ-----NCTHVVGHVRLAYVDLTDVSGNYSLDSLASNVTE 91
            |:.|               ..||.::     ||..:|.:      |..:.....:|||:..:|..
 Worm   419 IDHIQRTLYAVQHDKGIIRCKLRTMEAEESPNCVLIVNN------DALNAPKEITLDSVNGHVYT 477

  Fly    92 ISDYLMVYR-------CTGLISLQSIFPRLRIIRGQELLFDQYSLVVYENRNLRELGLVELLRIQ 149
            ::....|||       .||:.::.|:.....:.....:.||....::|.             .:|
 Worm   478 LNADNKVYRTEMVAFNATGIETVASLQYLQDMSPSNGIFFDVSKFLLYS-------------ALQ 529

  Fly   150 SGFIRVESNPLLCFVETVDWIYL---MGNATRQHFSLKHNRPQSQCPLCGSLSAD-----FEFIR 206
            :|.: :..||:      .|.:::   :|.|..|||.:|::........||...||     .|.::
 Worm   530 NGSM-MTLNPV------TDHVHIFKDVGYADIQHFRIKNDLIYWMKKKCGETDADENCIFAENLQ 587

  Fly   207 NSSERCWNVNTTQ-------------LRPQPPRLKDCPIACGLNGCDSAGKCCDHNCVTGCYSQN 258
            .|.|...|..|..             |:   ||:........|....:|....|.:......:|.
 Worm   588 RSEEDIPNKFTYSSSLMSFGVLEEILLK---PRITAVSTIAMLTSDKTARVSWDESNTLPFQAQG 649

  Fly   259 CSLCANYQGRMGCVNQCVASYELNKRRCIGHRECRELGRIPLIRGYQCVKKCPGN-QKEILVAKG 322
            .| ..|:            :|.|..             ..|.|..:..::....| :.:|.|..|
 Worm   650 SS-WRNF------------TYFLKV-------------TAPDITDFSPIEIYTSNTEMKIDVTPG 688

  Fly   323 -IIHCQVE-CNGDF----------------------HVKSAAD----LEVLQDCVTINGSLTIEL 359
             |.:.||: |:.||                      ..|..||    :::|.:.:..:.|:
 Worm   689 NIYNAQVQVCSDDFCSIPTSTSNTALPDLGDVVPFVFTKRQADDIISVDILGNIIPADDSV---- 749

  Fly   360 TNIKEKIVDALE--NALASVKEITGYLKVIHSAQLMSLTFLQNLDAIRG------DKLVENKYAL 416
                 |||:.|:  :.|.:..: |.||...||..:    |.:.||...|      |.|.....::
 Worm   750 -----KIVEKLQYPHVLDNTTK-TVYLAGDHSMGI----FKKYLDDTAGLPKPFKDGLFVEMMSI 804

  Fly   417 ------------YVVNNYHLE--------------------------------H----------- 426
                        |.:.:|.|.                                |
 Worm   805 MPARSIILIASSYKITSYRLPTTFDFEYFSCEEPLEACSEVMGISSDDTTGMVHFLTQARNGTIT 869

  Fly   427 IW---PPNHL---------VIIQRGTLFFHLNPRLCYEKIHQLQGSLKSGENISVADVSPNSNGE 479
            :|   |.|..         ::..|..|..|....|..:..|.:|    :.:.:.|.:|:  :..|
 Worm   870 LWESDPENRTPRDIASVPSIVPFRRFLILHDKMILVTKNNHIVQ----TDKKLKVVNVA--TELE 928

  Fly   480 RV--ICGDAVRSLNPKVEDLNSTAVRIILDYMDWEGMETLIGYSYHYKEAPVQ------NVTMYD 536
            ||  |......:::.|:|  .|..::.|      :|.:|.:.::.   ..|::      .|:::.
 Worm   929 RVDHILPLRYATISHKIE--FSDEIKFI------DGSKTNLQWTL---SPPLEAGTVLFKVSIFR 982

  Fly   537 GRHGCGHDNWLMDV-------VPNQ-------SRRHVISGLKPYTQYAYFVKTLTRTEYHIQIDA 587
            .:.| |.|..::.:       :|::       ::|..:| ::..|.:|..|  |.||..
 Worm   983 EKMG-GQDPPIITIQSETNFTIPSEVLEAWSSAQRFDVS-VQAMTPWATAV--LNRTGL------ 1037

  Fly   588 YSKIGYFQTLPDRP--SPV-LRIYGSSEIS-----SQILLHWWPPRRPNGVIKNYFVTAEKYNAT 644
                    |.|.:|  ||. |||:.:.:.:     :.|...|.||...||....|.|     |.|
 Worm  1038 --------TAPVKPPTSPTQLRIFATQQKTVDGPRALISFFWGPPSEWNGTPYQYIV-----NCT 1089

  Fly   645 KE---------AKDKNYVNVELENAKDIDCECAGVLPYYSGPQPDDEDYYNKEQITYE------- 693
            |:         ...:::.:..:::.| :.|:.|      :..:|.:...:: |.||.:
 Worm  1090 KDDGSWIGGPVTTSQSHYSFAVKSGK-VSCQAA------AANEPTNIGSFS-ELITIDSSELKPL 1146

  Fly   694 ------DALPNLIYVS-RNHDYRRKEFEKV-----INY-------EHLLSIKKDEEPTRP 734
                  |:..:||.:: ..|:..|:|..:|     :.|       |.|.:::|:.|..:|
 Worm  1147 VKLFAIDSTNSLISINDLAHEEPRRETRQVAQPVKLEYQAMAFIGEDLYAVRKEGESAQP 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_001287331.1	Recep_L_domain	58..173	CDD:279382	22/124 (18%)
		Furin-like	209..332	CDD:279142	24/138 (17%)
		Recep_L_domain	347..461	CDD:279382	30/188 (16%)
		FN3	491..578	CDD:214495	18/106 (17%)
rol-3	NP_001256097.1	FN3	1542..1636	CDD:238020
		fn3	1664..1749	CDD:278470
		STYKc	1966..2232	CDD:214568
		PTKc	1970..2233	CDD:270623

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870