Protein Alignment Sdr and Epha7

DIOPT Version :10

• Sequence 1: NP_650408.1
• Gene: Sdr / 41809
• FlyBaseID: FBgn0038279
• Length: 868
• Species: Drosophila melanogaster
• Sequence 2: NP_034271.3
• Gene: Epha7 / 13841
• MGIID: 95276
• Length: 998
• Species: Mus musculus
• Alignment Length: 204
• Identity: 46/204 - (22%)
• Similarity: 73/204 - (35%)
• Gaps: 57/204 - (27%)

  Fly   466 NISVADVS-----PNSNGERVICGDAVRSLNPKVEDLNSTAVRIILDYMDWEGMETL-----IGY 520
            ||:...||     |..||.|                 |....||:.....||..|.:     |||
Mouse   341 NINQTTVSLEWSPPADNGGR-----------------NDVTYRILCKRCSWEQGECVPCGSNIGY 388

  Fly   521 SYHYKEAPVQNVTMYDGRHGCGHDNWLMDVVPNQSRRHVISGLKPYTQYAYFVKTLTRTEYHIQI 585
            ...........||:.|   ...|.|:..:|       ..::|          |..|:|::   ::
Mouse   389 MPQQTGLEDNYVTVMD---LLAHANYTFEV-------EAVNG----------VSDLSRSQ---RL 430

  Fly   586 DAYSKIGYFQTLPDRPSPVLRIYGSSEISSQILLHWWPPRRPNGVIKNYFVTAEKYNATKEAKDK 650
            .|...|...|..|.:.|.|::   ...:...:.|.|..|..|||||..|.:   || ..|:.:::
Mouse   431 FAAVSITTGQAAPSQVSGVMK---ERVLQRSVQLSWQEPEHPNGVITEYEI---KY-YEKDQRER 488

  Fly   651 NYVNVELEN 659
            .|..::.::
Mouse   489 TYSTLKTKS 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sdr	NP_650408.1	Recep_L_domain	58..173	CDD:460032
		Furin-like	210..332	CDD:395614
		Recep_L_domain	347..461	CDD:460032
		FN3	491..578	CDD:214495	18/91 (20%)
Epha7	NP_034271.3	EphR_LBD_A7	30..206	CDD:198453
		FN3	<314..>549	CDD:442628	46/204 (23%)
		FN3	443..534	CDD:238020	16/62 (26%)
		EphA2_TM	565..630	CDD:464211
		PTKc_EphR_A	628..894	CDD:270651
		SAM_EPH-A7	919..988	CDD:188947
		PDZ-binding. /evidence=ECO:0000255	996..998