DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VhaPPA1-2 and VMA16

DIOPT Version :9

Sequence 1:	NP_650406.2	Gene:	VhaPPA1-2 / 41806	FlyBaseID:	FBgn0262514	Length:	212	Species:	Drosophila melanogaster
Sequence 2:	NP_011891.1	Gene:	VMA16 / 856421	SGDID:	S000001068	Length:	213	Species:	Saccharomyces cerevisiae

Alignment Length:	209	Identity:	99/209 - (47%)
Similarity:	136/209 - (65%)	Gaps:	13/209 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ISKMSFGLFFMLFVLGAASLGAVGIIFA--NVMVNMGERMGLGWFLYTSNPFLWSGMGIFLACAL 64
            :.|.||..|....||      .|.|::.  .:....|..:..|.||..::|::|:.:||.|...|
Yeast    12 LGKFSFSHFLYYLVL------IVVIVYGLYKLFTGHGSDINFGKFLLRTSPYMWANLGIALCVGL 70

  Fly    65 SVLGAASGIYMIGCSVAGGGVRSPRIKTKNLISVIFCEAVAIYGLITAILLSGNVNKFSSVRLIT 129
            ||:|||.||::.|.|:.|.|||:|||.||||||:||||.|||||||.||:.|..:...::..:.:
Yeast    71 SVVGAAWGIFITGSSMIGAGVRAPRITTKNLISIIFCEVVAIYGLIIAIVFSSKLTVATAENMYS 135

  Fly   130 DSTVMATNMFTGFATFGAGLCVGMVNVACGIAVGIVGSGAALADAANSALFVKILIVEIFGSAIG 194
            .|     |::||::.|.||:.||..|:.|||||||.|:.||::|||:||||||||::|||||.:|
Yeast   136 KS-----NLYTGYSLFWAGITVGASNLICGIAVGITGATAAISDAADSALFVKILVIEIFGSILG 195

  Fly   195 LFGLIVAIYMTSKA 208
            |.||||.:.|..||
Yeast   196 LLGLIVGLLMAGKA 209

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VhaPPA1-2	NP_650406.2	ATP-synt_C	56..166	CDD:294318	57/109 (52%)
VhaPPA1-2	NP_650406.2	ATP-synt_C	143..204	CDD:278563	38/60 (63%)
VMA16	NP_011891.1	ATP-synt_Vo_c_ATP6F_rpt1	59..121	CDD:349417	40/61 (66%)
VMA16	NP_011891.1	ATP-synt_Vo_c_ATP6F_rpt2	141..>192	CDD:349418	32/50 (64%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342071
Domainoid	1	1.000	87	1.000	Domainoid score	I1843
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	208	1.000	Inparanoid score	I822
Isobase	1	0.950	-	0	Normalized mean entropy	S432
OMA	1	1.010	-	-		QHG53850
OrthoFinder	1	1.000	-	-		FOG0002690
OrthoInspector	1	1.000	-	-		otm46750
orthoMCL	1	0.900	-	-		OOG6_102000
Panther	1	1.100	-	-	O	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2155
TreeFam	1	0.960	-	-
	13	12.710